Wright, George G. and Schomaker, Verner (1948) Studies on the Denaturation of Antibody. III. Kinetic Aspects of the Inactivation of Diphtheria Antitoxin by Urea. Journal of the American Chemical Society, 70 (1). pp. 356-364. ISSN 0002-7863. doi:10.1021/ja01181a111. https://resolver.caltech.edu/CaltechAUTHORS:20180724-121639493
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Abstract
In the present investigation we have studied the effects of pH, urea concentration, and temperature on the inactivation reaction, in order to explore the influence of these factors on its abnormalities. The experimental results are shown to be compatible with a simple kinetic mechanism.
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| Additional Information: | © 1948 American Chemical Society. Received July 2, 1947. This investigation was carried out with the aid of a grant from The Rockefeller Foundation. The authors are indebted to Professor Linus Pauling for suggestions and discussion, to J. Y. Chien for carrying out preliminary experiments on the effect of temperature, and to Sharp and Dohme, Glenolden, Pennsylvania, for supplying the antitoxin and toxin | ||||||
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| Issue or Number: | 1 | ||||||
| DOI: | 10.1021/ja01181a111 | ||||||
| Record Number: | CaltechAUTHORS:20180724-121639493 | ||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20180724-121639493 | ||||||
| Official Citation: | Studies on the Denaturation of Antibody. III. Kinetic Aspects of the Inactivation of Diphtheria Antitoxin by Urea George G. Wright and Verner Schomaker Journal of the American Chemical Society 1948 70 (1), 356-364 DOI: 10.1021/ja01181a111 | ||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||
| ID Code: | 88185 | ||||||
| Collection: | CaltechAUTHORS | ||||||
| Deposited By: | George Porter | ||||||
| Deposited On: | 24 Jul 2018 21:37 | ||||||
| Last Modified: | 16 Nov 2021 00:24 |
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