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Activation of RNA Synthesis Associated with Gastrulation

Bachvarova, R. and Davidson, E. H. and Allfrey, V. G. and Mirsky, A. E. (1966) Activation of RNA Synthesis Associated with Gastrulation. Proceedings of the National Academy of Sciences of the United States of America, 55 (2). pp. 358-365. ISSN 0027-8424. PMCID PMC224149.

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Gastrulation in the amphibian embryo marks the onset of widespread, de novo cell differentiation. In this communication we present the results of a radioautographic and biochemical study of gene activity as gastrulation takes place in Xenopus laevis. We have found that gene activation occurs abruptly within a 1-hr period preceding the onset of gastrulation and that most of the newly synthesized RNA resulting from this activation appears to be messenger RNA.

Item Type:Article
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Additional Information:Copyright © 1966 by the National Academy of Sciences. Communicated December 6, 1965. This investigation was supported in part by American Cancer Society grant E-334.
Funding AgencyGrant Number
American Cancer SocietyE-334
Issue or Number:2
PubMed Central ID:PMC224149
Record Number:CaltechAUTHORS:BACpnas66
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:8935
Deposited By: Archive Administrator
Deposited On:03 Oct 2007
Last Modified:02 Oct 2019 23:55

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