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Photoacoustic computed tomography without accurate ultrasonic transducer responses

Sheng, Qiwei and Wang, Kun and Xia, Jun and Zhu, Liren and Wang, Lihong V. and Anastasio, Mark A. (2015) Photoacoustic computed tomography without accurate ultrasonic transducer responses. In: Photons Plus Ultrasound: Imaging and Sensing 2015. Proceedings of SPIE. No.9323. Society of Photo-Optical Instrumentation Engineers , Bellingham, WA, Art. No. 932313. ISBN 9781628414134. https://resolver.caltech.edu/CaltechAUTHORS:20180907-103744023

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Abstract

Conventional photoacoustic computed tomography (PACT) image reconstruction methods assume that the object and surrounding medium are described by a constant speed-of-sound (SOS) value. In order to accurately recover fine structures, SOS heterogeneities should be quantified and compensated for during PACT reconstruction. To address this problem, several groups have proposed hybrid systems that combine PACT with ultrasound computed tomography (USCT). In such systems, a SOS map is reconstructed first via USCT. Consequently, this SOS map is employed to inform the PACT reconstruction method. Additionally, the SOS map can provide structural information regarding tissue, which is complementary to the functional information from the PACT image. We propose a paradigm shift in the way that images are reconstructed in hybrid PACT-USCT imaging. Inspired by our observation that information about the SOS distribution is encoded in PACT measurements, we propose to jointly reconstruct the absorbed optical energy density and SOS distributions from a combined set of USCT and PACT measurements, thereby reducing the two reconstruction problems into one. This innovative approach has several advantages over conventional approaches in which PACT and USCT images are reconstructed independently: (1) Variations in the SOS will automatically be accounted for, optimizing PACT image quality; (2) The reconstructed PACT and USCT images will possess minimal systematic artifacts because errors in the imaging models will be optimally balanced during the joint reconstruction; (3) Due to the exploitation of information regarding the SOS distribution in the full-view PACT data, our approach will permit high-resolution reconstruction of the SOS distribution from sparse array data.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1117/12.2081056DOIArticle
ORCID:
AuthorORCID
Wang, Lihong V.0000-0001-9783-4383
Anastasio, Mark A.0000-0002-3192-4172
Additional Information:© 2015 Society of Photo-Optical Instrumentation Engineers. This work was supported in part by NIH awards CA167446 and EB01696301.
Funders:
Funding AgencyGrant Number
NIHCA167446
NIHEB01696301
Series Name:Proceedings of SPIE
Issue or Number:9323
Record Number:CaltechAUTHORS:20180907-103744023
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20180907-103744023
Official Citation:Qiwei Sheng, Qiwei Sheng, Kun Wang, Kun Wang, Jun Xia, Jun Xia, Liren Zhu, Liren Zhu, Lihong V. Wang, Lihong V. Wang, Mark A. Anastasio, Mark A. Anastasio, } "Photoacoustic computed tomography without accurate ultrasonic transducer responses", Proc. SPIE 9323, Photons Plus Ultrasound: Imaging and Sensing 2015, 932313 (11 March 2015); doi: 10.1117/12.2081056; https://doi.org/10.1117/12.2081056
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:89448
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:08 Sep 2018 03:24
Last Modified:03 Oct 2019 20:16

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