A Caltech Library Service

Focusing light in scattering media by ultrasonically encoded wavefront shaping (SEWS)

Tay, Jian Wei and Lai, Puxiang and Suzuki, Yuta and Wang, Lihong V. (2014) Focusing light in scattering media by ultrasonically encoded wavefront shaping (SEWS). In: Photons Plus Ultrasound: Imaging and Sensing 2014. Proceedings of SPIE. No.8943. Society of Photo-optical Instrumentation Engineers (SPIE) , Bellingham, WA, Art. No. 89434P. ISBN 9780819498564.

[img] PDF - Published Version
See Usage Policy.


Use this Persistent URL to link to this item:


Wavefront distortion in scattering media can be compensated for using optical wavefront shaping. In this technique, a spatial light modulator (SLM) is used to apply a spatially distributed phase shift to the optical field. A genetic optimization algorithm was used to obtain the SLM pattern which best focuses light within the medium. The target volume is defined by using a focused ultrasound beam to encode light travelling within the acoustic focus. The ultrasonically-encoded light is measured and used as feedback to the algorithm, which then searches for the pattern which maximizes the encoded light intensity. We call this technique ultrasonically-encoded wavefront shaping (SEWS). Using SEWS, we focused light into a scattering medium consisting of ground glass diffuser and a gelatin phantom. The optical intensity at the target was increased by 11 times over the original intensity. These results were validated using fluorescent imaging at the ultrasonic focus.

Item Type:Book Section
Related URLs:
URLURL TypeDescription
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2014 Society of Photo-Optical Instrumentation Engineers (SPIE). This work was sponsored in part by the National Academies Keck Futures Initiative grant IS 13 and National Institute of Health grant DP1 EB016986 (NIH Director’s Pioneer Award).
Funding AgencyGrant Number
National Academies Keck Futures InitiativeIS 13
NIHDP1 EB016986
Subject Keywords:Optical Engineering, Wavefront Shaping, Turbidity Compensation, Ultrasound, Imaging, Spatial Light Modulator
Series Name:Proceedings of SPIE
Issue or Number:8943
Record Number:CaltechAUTHORS:20180911-164454484
Persistent URL:
Official Citation:Jian Wei Tay, Jian Wei Tay, Puxiang Lai, Puxiang Lai, Yuta Suzuki, Yuta Suzuki, Lihong V. Wang, Lihong V. Wang, } "Focusing light in scattering media by ultrasonically encoded wavefront shaping (SEWS)", Proc. SPIE 8943, Photons Plus Ultrasound: Imaging and Sensing 2014, 89434P (3 March 2014); doi: 10.1117/12.2037037;
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:89543
Deposited By: George Porter
Deposited On:12 Sep 2018 20:48
Last Modified:16 Nov 2021 00:36

Repository Staff Only: item control page