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Photoacoustic endoscopic imaging study of melanoma tumor growth in a rat colorectum in vivo

Li, Chiye and Yang, Joon-Mo and Chen, Ruimin and Zhang, Yu and Xia, Younan and Zhou, Qifa and Shung, K. Kirk and Wang, Lihong V. (2013) Photoacoustic endoscopic imaging study of melanoma tumor growth in a rat colorectum in vivo. In: Photons Plus Ultrasound: Imaging and Sensing 2013. Proceedings of SPIE. No.8581. Society of Photo-optical Instrumentation Engineers (SPIE) , Bellingham, WA, Art. No. 85810D. ISBN 9780819493507. http://resolver.caltech.edu/CaltechAUTHORS:20180914-150421069

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Abstract

We performed a photoacoustic endoscopic imaging study of melanoma tumor growth in a nude rat in vivo. After inducing the tumor at the colorectal wall of the animal, we monitored the tumor development in situ by using a photoacoustic endoscopic system. This paper introduces our experimental method for tumor inoculation and presents imaging results showing the morphological changes of the blood vasculature near the tumor region according to the tumor progress. Our study could provide insights for future studies on tumor development in small animals.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1117/12.2005470DOIArticle
ORCID:
AuthorORCID
Chen, Ruimin0000-0002-5338-359X
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2013 Society of Photo-Optical Instrumentation Engineers (SPIE). We thank Seema Dahlheimer for her attentive reading of the manuscript. This work was sponsored in part by National Institutes of Health grants R01 CA157277, R01 NS46214 (BRP), R01 EB000712, R01 EB008085, and U54 CA136398 (Network for Translational Research). L.W. has a financial interest in Microphotoacoustics, Inc. and Endra, Inc., which, however, did not support this work.
Funders:
Funding AgencyGrant Number
NIHR01 CA157277
NIHR01 NS46214
NIHR01 EB000712
NIHR01 EB008085
NIHU54 CA136398
Subject Keywords:Photoacoustic endoscopy, melanoma tumor, nude rat, colorectum
Record Number:CaltechAUTHORS:20180914-150421069
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20180914-150421069
Official Citation:Chiye Li, Chiye Li, Joon-Mo Yang, Joon-Mo Yang, Ruimin Chen, Ruimin Chen, Yu Zhang, Yu Zhang, Younan Xia, Younan Xia, Qifa Zhou, Qifa Zhou, K. Kirk Shung, K. Kirk Shung, Lihong V. Wang, Lihong V. Wang, } "Photoacoustic endoscopic imaging study of melanoma tumor growth in a rat colorectum in vivo", Proc. SPIE 8581, Photons Plus Ultrasound: Imaging and Sensing 2013, 85810D (4 March 2013); doi: 10.1117/12.2005470; https://doi.org/10.1117/12.2005470
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:89653
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:14 Sep 2018 22:41
Last Modified:14 Sep 2018 22:41

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