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Image reconstruction in photoacoustic tomography with heterogeneous media using an iterative method

Huang, Chao and Wang, Kun and Wang, Lihong V. and Anastasio, Mark A. (2013) Image reconstruction in photoacoustic tomography with heterogeneous media using an iterative method. In: Photons Plus Ultrasound: Imaging and Sensing 2013. Proceedings of SPIE. No.8581. Society of Photo-optical Instrumentation Engineers (SPIE) , Bellingham, WA, Art. No. 858106. ISBN 9780819493507.

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There remains an urgent need to develop effective photoacoustic computed tomography (PACT) image recon- struction methods for use with acoustically inhomogeneous media. Transcranial PACT brain imaging is an im- portant example of an emerging imaging application that would benefit greatly from this. Existing approaches to PACT image reconstruction in acoustically heterogeneous media are limited to weakly varying media, are computationally burdensome, and/or make impractical assumptions regarding the measurement geometry. In this work, we develop and investigate a full-wave approach to iterative image reconstruction in PACT for media possessing inhomogeneous speed-of-sound and mass density distributions. A key contribution of the work is the formulation of a procedure to implement a matched discrete forward and backprojection operator pair, which facilitates the application of a wide range of modern iterative image reconstruction algorithms. This presents the opportunity to employ application-specific regularization methods to mitigate image artifacts due to mea- surement data incompleteness and noise. Our results establish that the proposed image reconstruction method can effectively compensate for acoustic aberration and reduces artifacts in the reconstructed image.

Item Type:Book Section
Related URLs:
URLURL TypeDescription
Wang, Lihong V.0000-0001-9783-4383
Anastasio, Mark A.0000-0002-3192-4172
Additional Information:© 2013 Society of Photo-Optical Instrumentation Engineers (SPIE). This work was supported in part by NIH awards EB010049 and CA167446.
Funding AgencyGrant Number
NIHR01 EB010049
Subject Keywords:Photoacoustic tomography, optoacoustic tomography, thermoacoustic tomography, iterative image reconstruction, acoustic heterogeneity, k-space pseudospectral method
Series Name:Proceedings of SPIE
Issue or Number:8581
Record Number:CaltechAUTHORS:20180914-150421466
Persistent URL:
Official Citation:Chao Huang, Chao Huang, Kun Wang, Kun Wang, Lihong V. Wang, Lihong V. Wang, Mark A. Anastasio, Mark A. Anastasio, } "Image reconstruction in photoacoustic tomography with heterogeneous media using an iterative method", Proc. SPIE 8581, Photons Plus Ultrasound: Imaging and Sensing 2013, 858106 (4 March 2013); doi: 10.1117/12.2007072;
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:89657
Deposited By: George Porter
Deposited On:14 Sep 2018 23:03
Last Modified:16 Nov 2021 00:37

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