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On the interactions of lipids and proteins in the red blood cell membrane

Glaser, Michael and Simpkins, Henry and Singer, S. J. and Sheetz, Michael and Chan, Sunney I. (1970) On the interactions of lipids and proteins in the red blood cell membrane. Proceedings of the National Academy of Sciences of the United States of America, 65 (3). pp. 721-728. ISSN 0027-8424. PMCID PMC282966. https://resolver.caltech.edu/CaltechAUTHORS:GLApnas70

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Abstract

The effects of temperature and of the action of a purified phospholipase C enzyme preparation on human red blood cell membranes has been investigated by chemical analyses, circular dichroism, and proton magnetic resonance measurements. The results indicate that a substantial fraction of the phospholipids and the proteins of the membranes can change structure independently of one another, suggesting a mosaic pattern for the organization of the lipids and proteins in membranes.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC282966/PubMed CentralArticle
http://www.pnas.org/cgi/content/abstract/65/3/721OtherUNSPECIFIED
http://www.pnas.org/cgi/content/abstract/65/3/721OtherUNSPECIFIED
ORCID:
AuthorORCID
Chan, Sunney I.0000-0002-5348-2723
Additional Information:© 1970 by the National Academy of Sciences. Communicated December 12, 1969. This work was supported in part by U.S.P.H.S. grant GM-15971 to S.J. Singer and U.S.P.H.S. grant GM-14523 and NSF grant GP-8540 to S.I. Chan (Caltech). [M.S. was a] National Institute of Health Predoctoral Trainee, 1969-1970. A.A. Noyes Laboratory of Chemical Physics, Contribution No. 3977.
Funders:
Funding AgencyGrant Number
NIH Predoctoral FellowshipUNSPECIFIED
NIHGM-15971
NIHGM-14523
NSFGP-8540
Other Numbering System:
Other Numbering System NameOther Numbering System ID
Arthur Amos Noyes Laboratory of Chemical Physics3977
Issue or Number:3
PubMed Central ID:PMC282966
Record Number:CaltechAUTHORS:GLApnas70
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:GLApnas70
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:8966
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:09 Oct 2007
Last Modified:02 Oct 2019 23:56

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