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Förster resonance energy transfer photoacoustic microscopy

Wang, Yu and Wang, Lihong V. (2013) Förster resonance energy transfer photoacoustic microscopy. In: Photons Plus Ultrasound: Imaging and Sensing 2013. Proceedings of SPIE. No.8581. Society of Photo-optical Instrumentation Engineers (SPIE) , Bellingham, WA, Art. no. 85812E. ISBN 9780819493507. https://resolver.caltech.edu/CaltechAUTHORS:20180917-094549257

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Abstract

Förster resonance energy transfer (FRET) provides fluorescence signals sensitive to intra- and inter-molecular distances in the 1-10 nm range. Widely applied in the optical imaging environment, FRET enables visualization of physicochemical processes in molecular interactions and conformation changes. We reported photoacoustic imaging of FRET, based on non-radiative decay that produces heat and subsequent acoustic waves. The experimental results show that photoacoustic imaging offers better penetration into scattering biological tissue. Through its ability to three-dimensionally image tissue with scalable resolution, photoacoustic microscopy provides a beneficial biomedical tool to broaden the in vivo application of the FRET technique.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1117/12.2004150DOIArticle
ORCID:
AuthorORCID
Wang, Yu0000-0003-3589-9274
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2013 Society of Photo-Optical Instrumentation Engineers (SPIE).
Subject Keywords:Förster resonance energy transfer, FRET, Photoacoustic imaging
Series Name:Proceedings of SPIE
Issue or Number:8581
DOI:10.1117/12.2004150
Record Number:CaltechAUTHORS:20180917-094549257
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20180917-094549257
Official Citation:Yu Wang, Yu Wang, Lihong V. Wang, Lihong V. Wang, } "Förster resonance energy transfer photoacoustic microscopy", Proc. SPIE 8581, Photons Plus Ultrasound: Imaging and Sensing 2013, 85812E (4 March 2013); doi: 10.1117/12.2004150; https://doi.org/10.1117/12.2004150
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:89670
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:17 Sep 2018 18:23
Last Modified:16 Nov 2021 00:37

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