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Digital reflection-mode time-reversed ultrasonically encoded (TRUE) optical focusing

Suzuki, Yuta and Tay, Jian Wei and Yang, Qiang and Wang, Lihong (2014) Digital reflection-mode time-reversed ultrasonically encoded (TRUE) optical focusing. In: Photons Plus Ultrasound: Imaging and Sensing 2014. Proceedings of SPIE. No.8943. Society of Photo-optical Instrumentation Engineers (SPIE) , Bellingham, WA, Art. No. 89431B. ISBN 9780819498564.

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To achieve localized light delivery beyond turbid layers, TRUE optical focusing has been previously implemented by both analog and digital devices. The digital scheme offers a higher energy gain than the analog version. In many biological applications, the reflection-mode configuration, which uses backscattered light from the sample, is more suitable than the transmission-mode configuration. Although reflection-mode analog TRUE focusing has been demonstrated, its digital implementation has not been explored. Here, we report a reflection-mode digital TRUE focusing to concentrate light through a turbid layer. Further, by simply moving the ultrasound focus, we show the system's dynamic focusing capability.

Item Type:Book Section
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Wang, Lihong0000-0001-9783-4383
Additional Information:© 2014 Society of Photo-Optical Instrumentation Engineers (SPIE). This work was sponsored in part by National Institutes of Health grants DP1 EB016986 (NIH Director’s Pioneer Award) and R01 CA186567 (NIH Director’s Transformative Research Award). L.W. has a financial interest in Microphotoacoustics, Inc. and Endra, Inc., which, however, did not support this work.
Funding AgencyGrant Number
NIHDP1 EB016986
NIHR01 CA186567
Subject Keywords:optical focusing, ultrasound modulation, optical imaging, phase conjugation, time reversal, photorefractive material
Series Name:Proceedings of SPIE
Issue or Number:8943
Record Number:CaltechAUTHORS:20180917-151059460
Persistent URL:
Official Citation:Yuta Suzuki, Yuta Suzuki, Jian Wei Tay, Jian Wei Tay, Qiang Yang, Qiang Yang, Lihong Wang, Lihong Wang, } "Digital reflection-mode time-reversed ultrasonically encoded (TRUE) optical focusing", Proc. SPIE 8943, Photons Plus Ultrasound: Imaging and Sensing 2014, 89431B (3 March 2014); doi: 10.1117/12.2037952;
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:89688
Deposited By: George Porter
Deposited On:17 Sep 2018 22:45
Last Modified:16 Nov 2021 00:37

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