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Improving the imaging ability of ultrasound-modulated optical tomography with spectral-hole burning

Xu, Xiao and Liu, Honglin and Wang, Lihong V. (2011) Improving the imaging ability of ultrasound-modulated optical tomography with spectral-hole burning. In: Advances in Photonics of Quantum Computing, Memory, and Communication IV. Proceedings of SPIE. No.7948. Society of Photo-Optical Instrumentation Engineers , Bellingham, WA, Art. No. 794803. ISBN 9780819484857. https://resolver.caltech.edu/CaltechAUTHORS:20180918-132943189

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Abstract

Ultrasound-modulated optical tomography is a hybrid imaging technique based on detection of the diffused light modulated by a focused ultrasonic wave inside a scattering medium. With the combined advantages of ultrasonic resolution and optical contrast, UOT is ideal for deep tissue imaging. Its growth in popularity and application, however, is hindered by the low efficiency in detecting the modulated diffused photons. Research activities on UOT have therefore been centered on improving its signal detection efficiency by exploring various technical solutions. A prime example is the use of spectral-hole burning (SHB) in UOT. By applying SHB crystal as a spectral filter, one modulation sideband of the diffused light can be efficiently selected while all the other frequency components are strongly suppressed. Immune to both the spatial and temporal incoherence of the signal with a high enough on/off ratio, SHB can boost the UOT imaging ability dramatically and push it towards practical applications. We compare SHB with the other technologies that have been applied to UOT, and identify the unique features that make SHB a preferable tool for UOT. We also discuss the desired improvements from the SHB side, which will help UOT pave the way from research to everyday life.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1117/12.873999DOIArticle
ORCID:
AuthorORCID
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2011 Society of Photo-Optical Instrumentation Engineers. This research has been funded in part by the National Institutes of Health grants R01 EB000712 and U54 CA136398.
Funders:
Funding AgencyGrant Number
NIHR01 EB000712
NIHU54 CA136398
Subject Keywords:Optical Imaging, Optical Tomography, Tissue Optics, Spectral-Hole Burning, Ultrasound-modulated Optical Tomography, UOT, Optical Memory
Series Name:Proceedings of SPIE
Issue or Number:7948
Record Number:CaltechAUTHORS:20180918-132943189
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20180918-132943189
Official Citation:Xiao Xu, Xiao Xu, Honglin Liu, Honglin Liu, Lihong V. Wang, Lihong V. Wang, } "Improving the imaging ability of ultrasound-modulated optical tomography with spectral-hole burning", Proc. SPIE 7948, Advances in Photonics of Quantum Computing, Memory, and Communication IV, 794803 (10 February 2011); doi: 10.1117/12.873999; https://doi.org/10.1117/12.873999
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:89704
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:18 Sep 2018 20:42
Last Modified:03 Oct 2019 20:18

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