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Photoacoustic quantification of the optical absorption cross-sections of gold nanostructures

Kim, Chulhong and Cho, Eun Chul and Zhou, Fei and Cobley, Claire M. and Song, Kwang Hyun and Chen, Jingyi and Li, Zhi-Yuhan and Xia, Younan and Wang, Lihong V. (2010) Photoacoustic quantification of the optical absorption cross-sections of gold nanostructures. In: Photons Plus Ultrasound: Imaging and Sensing 2010. Proceedings of SPIE. No.7564. Society of Photo-optical Instrumentation Engineers (SPIE) , Bellingham, WA, Art. No. 756430. ISBN 9780819479600.

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This study demonstrates a method for measuring the optical absorption cross-sections (σ_a) of Au-Ag nanocages and Au nanorods using photoacoustic (PA) sensing. PA signals are directly proportional to the absorption coefficient (μ_a) of the nanostructure. For each type of nanostructure, we first obtained μa from the PA signal by benchmarking against a linear calibration curve (PA signal vs. μ_a) derived from a set of methylene blue solutions with different concentrations. We then calculated σ_a by dividing the μ_a by the corresponding concentration of the Au nanostructure. Additionally, we obtained the extinction cross-section (σ_e, sum of absorption and scattering cross-sections) from the extinction spectrum recorded using a conventional UV-vis-NIR spectrometer. From the measurements of σ_a and σ_e, we were able to easily derive both the absorption and scattering cross-sections for each type of gold nanostructure. This method can potentially provide the optical absorption and scattering properties of gold nanostructures and other types of nanomaterials.

Item Type:Book Section
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Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2010 Society of Photo-Optical Instrumentation Engineers (SPIE). This work was supported in part by grants from National Institutes of Health (R01 EB000712, R01 EB008085, R01 NS46214, and U54 CA136398 -- the Network for Translational Research -- to L.V.W.). L.V.W. has a financial interest in Endra, Inc., which, however, did not support this work. Y.X. thanks the National Institutes of Health for a 2006 Director’s Pioneer Award (DP1 OD000798-04). Z.Y.L. was supported by the National Natural Science Foundation of China (60736041 and 10874238). E.C.C. was also partially supported by a fellowship award from the Korea Research Foundation (KRF-2007-357-D00070) funded by the Korean Government.
Funding AgencyGrant Number
NIHR01 EB000712
NIHR01 EB008085
NIHR01 NS46214
NIHU54 CA136398
NIHDP1 OD000798-04
National Natural Science Foundation of China60736041
National Natural Science Foundation of China10874238
National Research Foundation of KoreaKRF-2007-357-D00070
Subject Keywords:Photoacoustic tomography, gold nanoparticles, optical absorption cross-sections, optical scattering cross-sections
Series Name:Proceedings of SPIE
Issue or Number:7564
Record Number:CaltechAUTHORS:20180918-140708773
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Official Citation:Chulhong Kim, Chulhong Kim, Eun Chul Cho, Eun Chul Cho, Fei Zhou, Fei Zhou, Claire M. Cobley, Claire M. Cobley, Kwang Hyun Song, Kwang Hyun Song, Jingyi Chen, Jingyi Chen, Zhi-Yuhan Li, Zhi-Yuhan Li, Younan Xia, Younan Xia, Lihong V. Wang, Lihong V. Wang, } "Photoacoustic quantification of the optical absorption cross-sections of gold nanostructures", Proc. SPIE 7564, Photons Plus Ultrasound: Imaging and Sensing 2010, 756430 (23 February 2010); doi: 10.1117/12.843554;
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:89716
Deposited By: George Porter
Deposited On:19 Sep 2018 23:16
Last Modified:03 Oct 2019 20:18

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