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Multi-contrast photoacoustic microscopy

Hu, S. and Sohn, R. and Lu, Z.-H. and Soetikno, B. and Zhong, Q. and Yao, J. and Maslov, K. and Arbeit, J. M. and Wang, L. V. (2012) Multi-contrast photoacoustic microscopy. In: Photons Plus Ultrasound: Imaging and Sensing 2012. Proceedings of SPIE. No.8223. Society of Photo-optical Instrumentation Engineers (SPIE) , Bellingham, WA, Art. No. 822310. ISBN 9780819488664. https://resolver.caltech.edu/CaltechAUTHORS:20180918-140709332

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Abstract

We developed multi-contrast photoacoustic microscopy (PAM) for in vivo anatomical, functional, metabolic, and molecular imaging. This technical innovation enables comprehensive understanding of the tumor microenvironment. With multi-contrast PAM, we longitudinally determined tumor vascular anatomy, blood flow, oxygen saturation of hemoglobin, and oxygen extraction fraction.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1117/12.909754DOIArticle
ORCID:
AuthorORCID
Wang, L. V.0000-0001-9783-4383
Additional Information:© 2012 Society of Photo-Optical Instrumentation Engineers (SPIE). This work was sponsored by National Institutes of Health Grants R01 EB000712, R01 EB008085, R01 CA134539, U54 CA136398, R01 CA157277, R01 EB010049, and R01 CA159959. L.V.W. has financial interests in Microphotoacoustics, Inc. and Endra, Inc., which, however, did not support this work.
Funders:
Funding AgencyGrant Number
NIHR01 EB000712
NIHR01 EB008085
NIHR01 CA134539
NIHU54 CA136398
NIHR01 CA157277
NIHR01 EB010049
NIHR01 CA159959
Subject Keywords:Optical-resolution photoacoustic microscopy, vascular anatomy, hemoglobin oxygen saturation, oxygen extraction fraction, tumor microenvironment
Series Name:Proceedings of SPIE
Issue or Number:8223
Record Number:CaltechAUTHORS:20180918-140709332
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20180918-140709332
Official Citation:S. Hu, S. Hu, R. Sohn, R. Sohn, Z.-H. Lu, Z.-H. Lu, B. Soetikno, B. Soetikno, Q. Zhong, Q. Zhong, J. Yao, J. Yao, K. Maslov, K. Maslov, J. M. Arbeit, J. M. Arbeit, L. V. Wang, L. V. Wang, } "Multi-contrast photoacoustic microscopy", Proc. SPIE 8223, Photons Plus Ultrasound: Imaging and Sensing 2012, 822310 (15 March 2012); doi: 10.1117/12.909754; https://doi.org/10.1117/12.909754
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:89722
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:19 Sep 2018 21:16
Last Modified:03 Oct 2019 20:18

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