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Mobility and transverse flow visualization using phase variance contrast with spectral domain optical coherence tomography

Fingler, Jeff and Schwartz, Dan and Yang, Changhuei and Fraser, Scott E. (2007) Mobility and transverse flow visualization using phase variance contrast with spectral domain optical coherence tomography. Optics Express, 15 (20). pp. 12636-12653. ISSN 1094-4087. https://resolver.caltech.edu/CaltechAUTHORS:FINoe07

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Abstract

Phase variance-based motion contrast is demonstrated using two phase analysis methods in a spectral domain optical coherence tomography system. Mobility contrast is demonstrated for an intensity matched Intralipid solution placed without flow within agarose wells. Vasculature oriented transversely to the imaging direction has been imaged for 3-4 dpf in vivo zebrafish using the phase variance contrast methods. 2D phase variance contrast images are demonstrated with imaging times only 25% higher than a Doppler flow image with comparable statistics. En face images created by integrating depth regions of 3D zebrafish intensity and phase variance contrast data demonstrate vasculature consistent with expected images.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://www.opticsinfobase.org/abstract.cfm?URI=oe-15-20-12636OtherUNSPECIFIED
ORCID:
AuthorORCID
Fraser, Scott E.0000-0002-5377-0223
Additional Information:© 2007 Optical Society of America. Original Manuscript: May 11, 2007. Manuscript Accepted: September 13, 2007. Revised Manuscript: September 11, 2007. Published: September 18, 2007. Authors would like to thank Carl Zeiss Meditec for their help in creating the imaging system. Further acknowledgements go out to Le Trinh and Julien Vermot for their help with the zebrafish work.
Subject Keywords:Optical coherence tomography, Phase measurement
Issue or Number:20
Record Number:CaltechAUTHORS:FINoe07
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:FINoe07
Official Citation:J. Fingler, D. Schwartz, C. Yang, and S. E. Fraser, "Mobility and transverse flow visualization using phase variance contrast with spectral domain optical coherence tomography," Opt. Express 15, 12636-12653 (2007) http://www.opticsinfobase.org/abstract.cfm?URI=oe-15-20-12636
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:8981
Collection:CaltechAUTHORS
Deposited By: Archive Administrator
Deposited On:11 Oct 2007
Last Modified:02 Oct 2019 23:56

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