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Continuous-wave photoacoustic microscopy

Maslov, Konstantin and Wang, Lihong V. (2007) Continuous-wave photoacoustic microscopy. In: Photons Plus Ultrasound: Imaging and Sensing 2007: The Eighth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics. Proceedings of SPIE. No.6437. Society of Photo-optical Instrumentation Engineers (SPIE) , Bellingham, WA, Art. No. 64370P. ISBN 9780819465504. https://resolver.caltech.edu/CaltechAUTHORS:20180921-100902279

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Abstract

We have built a photoacoustic microscope (PAM) using an amplitude-modulated continuous-wave (CW) laser source, which is an inexpensive 120-mW laser diode. By using a bowl-shaped piezoelectric transducer, whose numerical aperture is 0.85 and resonance frequency is 2.45 MHz, we have experimentally demonstrated a lateral resolution of 600 µm, an axial resolution of 700 µm, and a signal-to-noise ratio (SNR) as high as 43 dB. Although the SNR in the CW PAM system is an order of magnitude worse than that of the pulsed-laser-based PAM system, CW PAM shows potential for biomedical applications as it uses durable and inexpensive semiconductor lasers, which will significantly reduce operation costs of the PAM systems.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1117/12.702240DOIArticle
ORCID:
AuthorORCID
Maslov, Konstantin0000-0003-3408-8840
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2007 Society of Photo-Optical Instrumentation Engineers (SPIE). This project is sponsored by National Institutes of Health grants R01 EB000712 and R01 NS46214.
Funders:
Funding AgencyGrant Number
NIHR01 EB000712
NIHR01 NS46214
Subject Keywords:medical and biological imaging, photoacoustic imaging, microscopy
Series Name:Proceedings of SPIE
Issue or Number:6437
DOI:10.1117/12.702240
Record Number:CaltechAUTHORS:20180921-100902279
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20180921-100902279
Official Citation:Konstantin Maslov, Konstantin Maslov, Lihong V. Wang, Lihong V. Wang, } "Continuous-wave photoacoustic microscopy", Proc. SPIE 6437, Photons Plus Ultrasound: Imaging and Sensing 2007: The Eighth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics, 64370P (13 February 2007); doi: 10.1117/12.702240; https://doi.org/10.1117/12.702240
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:89833
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:26 Sep 2018 23:14
Last Modified:16 Nov 2021 00:38

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