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Noninvasive in-vivo optical properties of skin tumors

Garcia-Uribe, Alejandro and Smith, Elizabeth B. and Zou, Jun and Duvic, Madeleine and Wang, Lihong V. (2009) Noninvasive in-vivo optical properties of skin tumors. In: Optical Interactions with Tissue and Cells XX. Proceedings of SPIE. No.7175. Society of Photo-optical Instrumentation Engineers (SPIE) , Bellingham, WA, Art. No. 717506. ISBN 9780819474216.

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This paper presents a study for in-vivo estimation of optical properties of pigmented skin tumor by oblique incidence diffuse reflectance spectroscopy. The developed system has been tested in clinical conditions to compare the optical properties of melanomas, dysplastic nevi and common nevi. The spatio-spectral data are collected in the wavelength range of 455 to 765 nm from 96 pigmented skin lesions including 10 histopathologically diagnosed as melanoma, 67 as dysplastic nevi and 19 lesions as common nevi. The preliminary results indicate significantly larger average reduced scattering coefficient spectra for malignant and dysplastic lesions than for benign common nevi.

Item Type:Book Section
Related URLs:
URLURL TypeDescription
Zou, Jun0000-0002-9543-6135
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2009 Society of Photo-Optical Instrumentation Engineers (SPIE). The authors thank Dr. Mays, Dr. Hymens and Dr. Mansfield and the staff from the “Melanoma and Skin Center” at the University of Texas M. D. Anderson Cancer Center for their help during the data collection. This project is sponsored by National Institute of Health grant R01 CA106728.
Funding AgencyGrant Number
NIHR01 CA106728
Subject Keywords:Absorption coefficient, scattering coefficient, spectroscopy, skin cancer, melanoma
Series Name:Proceedings of SPIE
Issue or Number:7175
Record Number:CaltechAUTHORS:20180921-100905692
Persistent URL:
Official Citation:Alejandro Garcia-Uribe, Alejandro Garcia-Uribe, Elizabeth B. Smith, Elizabeth B. Smith, Jun Zou, Jun Zou, Madeleine Duvic, Madeleine Duvic, Lihong V. Wang, Lihong V. Wang, } "Noninvasive in-vivo optical properties of skin tumors", Proc. SPIE 7175, Optical Interactions with Tissue and Cells XX, 717506 (24 February 2009); doi: 10.1117/12.808397;
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:89868
Deposited By: George Porter
Deposited On:24 Sep 2018 15:48
Last Modified:09 Mar 2020 13:19

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