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A fast 512-element ring array photoacoustic imaging system for small animals

Gamelin, John and Maurudis, Anastasios and Aguirre, Andres and Huang, Fei and Guo, Puyun and Wang, Lihong V. and Zhu, Quing (2009) A fast 512-element ring array photoacoustic imaging system for small animals. In: Photons Plus Ultrasound: Imaging and Sensing 2009. Proceedings of SPIE. No.7177. Society of Photo-optical Instrumentation Engineers (SPIE) , Bellingham, WA, Art. No. 71770B. ISBN 9780819474230. https://resolver.caltech.edu/CaltechAUTHORS:20180921-100906012

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Abstract

A 512-element photoacoustic tomography system for small animal imaging using a ring ultrasound array has been developed. The system features a 5 MHz piezocomposite transducer array formed into a complete circular aperture. Custom receiver electronics consisting of dedicated preamplifiers, 8:1 multiplexed post-amplifiers, and a 64-channel data acquisition module provide full tomographic imaging at up to 8 frames/second. We present details of the system design along with characterization results of the resolution, imaging volume, and sensitivity. Small animal imaging performance is demonstrated through images of mice brain vasculature at different depths and real-time spectroscopic scans. This system enables real-time tomographic imaging for functional photoacoustic studies for the first time.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1117/12.812406DOIArticle
ORCID:
AuthorORCID
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2009 Society of Photo-Optical Instrumentation Engineers (SPIE). We acknowledge partial support from NIH grants NIH R01EB002136 and the Patrick and Catherine Weldon Donaghue Research Foundation.
Funders:
Funding AgencyGrant Number
NIHR01 EB002136
Patrick and Catherine Weldon Donaghue Research FoundationUNSPECIFIED
Subject Keywords:Photoacoustic tomography, real-time imaging, reconstruction, backprojection
Series Name:Proceedings of SPIE
Issue or Number:7177
Record Number:CaltechAUTHORS:20180921-100906012
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20180921-100906012
Official Citation:John Gamelin, John Gamelin, Anastasios Maurudis, Anastasios Maurudis, Andres Aguirre, Andres Aguirre, Fei Huang, Fei Huang, Puyun Guo, Puyun Guo, Lihong V. Wang, Lihong V. Wang, Quing Zhu, Quing Zhu, } "A fast 512-element ring array photoacoustic imaging system for small animals", Proc. SPIE 7177, Photons Plus Ultrasound: Imaging and Sensing 2009, 71770B (24 February 2009); doi: 10.1117/12.812406; https://doi.org/10.1117/12.812406
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:89871
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:24 Sep 2018 15:58
Last Modified:03 Oct 2019 20:20

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