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Signal and noise in ultrasound-modulated optical tomography: a Monte Carlo study

Yao, Gang and Wang, Lihong V. (2004) Signal and noise in ultrasound-modulated optical tomography: a Monte Carlo study. In: Photons Plus Ultrasound: Imaging and Sensing. Proceedings of SPIE. No.5320. Society of Photo-optical Instrumentation Engineers (SPIE) , Bellingham, WA, pp. 156-163. ISBN 9780819452283. https://resolver.caltech.edu/CaltechAUTHORS:20180927-114226717

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Abstract

Ultrasound-modulated optical tomography in inhomogeneous scattering media was studied using a Monte Carlo modeling technique. The contributions from two different modulation mechanisms were included in the simulation. The differences between embedded absorption and scattering objects in the ultrasound-modulated optical signals were compared. The effects of neighboring inhomogeneity and background optical properties on the ultrasound-modulated optical signals were also studied. We analyzed the signal-to-noise ratio in the experiment and found that the major noise source is the speckle noise caused by small particle movement within the biological tissue sample. This effect was studied by incorporating a Brownian motion factor in the simulation.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1117/12.532847DOIArticle
ORCID:
AuthorORCID
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2004 Society of Photo-Optical Instrumentation Engineers (SPIE). This project was sponsored by a Summer Faculty Resaerch Fellowship support (for Yao Gang) from University of Missouri-Columbia; and in part (for Wang) by National Institutes of Health grants R29 CA68562 and R01 CA71980, National Science Foundation grant BES-9734491, and Texas Higher Education Coordinating Board grant 000512-0063-2001.
Funders:
Funding AgencyGrant Number
University of Missouri-ColumbiaUNSPECIFIED
NIHR29 CA68562
NIHR01 CA71980
NSFBES-9734491
Texas Higher Education Coordinating Board000512-0063-2001
Subject Keywords:Ultrasound modulated optical tomography, Monte-Carlo, Contrast, Noise
Series Name:Proceedings of SPIE
Issue or Number:5320
DOI:10.1117/12.532847
Record Number:CaltechAUTHORS:20180927-114226717
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20180927-114226717
Official Citation:Gang Yao, Gang Yao, Lihong V. Wang, Lihong V. Wang, } "Signal and noise in ultrasound-modulated optical tomography: a Monte Carlo study", Proc. SPIE 5320, Photons Plus Ultrasound: Imaging and Sensing, (12 July 2004); doi: 10.1117/12.532847; https://doi.org/10.1117/12.532847
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:90028
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:31 Oct 2018 13:58
Last Modified:16 Nov 2021 00:40

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