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Optical and mechanical properties in photorefractive crystal based ultrasound-modulated optical tomography

Zhang, Huiliang and Xu, Xiao and Qing, De-Kui and Hemmer, Philip and Wang, Lihong V. (2006) Optical and mechanical properties in photorefractive crystal based ultrasound-modulated optical tomography. In: Photons Plus Ultrasound: Imaging and Sensing 2006: The Seventh Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics. Proceedings of SPIE. No.6086. Society of Photo-optical Instrumentation Engineers (SPIE) , Bellingham, WA, Art. No. 608616. ISBN 9780819461285. https://resolver.caltech.edu/CaltechAUTHORS:20181107-133916938

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Abstract

Ultrasound-modulated optical tomography (UOT) is a new technique that combines laser light and ultrasound to provide images with good optical contrast and good ultrasound resolution in soft biological tissue. We improve the method proposed by Murray et al to obtain UOT images in thick biological tissues with the use of photorefractive crystal based interferometers. It is found that a long ultrasound burst (on the order of a millisecond) can improve the signal-to-noise ratio dramatically. Also with a long ultrasound burst, the response of the acoustic radiation force impulses can be clearly observed in the UOT signal, which will help to acquire images that record both the optical and mechanical properties of biological soft tissues.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1117/12.646155DOIArticle
ORCID:
AuthorORCID
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2006 Society of Photo-optical Instrumentation Engineers (SPIE). We thank Chul Hong Kim for assistance with experiments measurements. We also appreciate Sava Sakadžić and Roger Zemp for fruitful scientific discussions. This research was supported by the National Institute of Health grant R33 CA094267 and AFOSR FA9550-04-1-0247.
Funders:
Funding AgencyGrant Number
NIHR33 CA094267
Air Force Office of Scientific Research (AFOSR)FA9550-04-1-0247
Subject Keywords:ultrasound-modulated optical tomography, photorefractive, acoustic radiation force
Series Name:Proceedings of SPIE
Issue or Number:6086
Record Number:CaltechAUTHORS:20181107-133916938
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20181107-133916938
Official Citation:Huiliang Zhang, Xiao Xu, De-Kui Qing, Philip Hemmer, Lihong V. Wang, } "Optical and mechanical properties in photorefractive crystal based ultrasound-modulated optical tomography", Proc. SPIE 6086, Photons Plus Ultrasound: Imaging and Sensing 2006: The Seventh Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics, 608616 (6 March 2006); doi: 10.1117/12.646155; https://doi.org/10.1117/12.646155
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:90722
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:07 Nov 2018 21:53
Last Modified:03 Oct 2019 20:28

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