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On joint maximum-likelihood estimation of PCR efficiency and initial amount of target

Vikalo, H. and Hassibi, B. and Hassibi, A. (2007) On joint maximum-likelihood estimation of PCR efficiency and initial amount of target. In: IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS 2006), College Station, TX, 28-30 May 2006. IEEE , Piscataway, NJ, pp. 47-48. ISBN 1-4244-0385-5. https://resolver.caltech.edu/CaltechAUTHORS:VIKgensips06

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Abstract

We consider the problem of estimating unknown parameters of the real-time polymerase chain reaction (RTPCR) from noisy observations. The joint ML estimator of the RT-PCR efficiency and the initial number of DNA target molecules is derived. The mean-square error performance of the estimator is studied via simulations. The simulation results indicate that the proposed estimator significantly outperforms a competing technique.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1109/GENSIPS.2006.353149DOIUNSPECIFIED
Additional Information:© Copyright 2006 IEEE. Reprinted with permission. [Posted online: 2007-04-30]
Record Number:CaltechAUTHORS:VIKgensips06
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:VIKgensips06
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:9074
Collection:CaltechAUTHORS
Deposited By: Archive Administrator
Deposited On:25 Oct 2007
Last Modified:02 Oct 2019 23:57

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