Vikalo, H. and Hassibi, B. and Hassibi, A. (2007) On joint maximum-likelihood estimation of PCR efficiency and initial amount of target. In: IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS 2006), College Station, TX, 28-30 May 2006. IEEE , Piscataway, NJ, pp. 47-48. ISBN 1-4244-0385-5. https://resolver.caltech.edu/CaltechAUTHORS:VIKgensips06
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Abstract
We consider the problem of estimating unknown parameters of the real-time polymerase chain reaction (RTPCR) from noisy observations. The joint ML estimator of the RT-PCR efficiency and the initial number of DNA target molecules is derived. The mean-square error performance of the estimator is studied via simulations. The simulation results indicate that the proposed estimator significantly outperforms a competing technique.
| Item Type: | Book Section | ||||||
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| Additional Information: | © Copyright 2006 IEEE. Reprinted with permission. [Posted online: 2007-04-30] | ||||||
| DOI: | 10.1109/GENSIPS.2006.353149 | ||||||
| Record Number: | CaltechAUTHORS:VIKgensips06 | ||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:VIKgensips06 | ||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||
| ID Code: | 9074 | ||||||
| Collection: | CaltechAUTHORS | ||||||
| Deposited By: | Archive Administrator | ||||||
| Deposited On: | 25 Oct 2007 | ||||||
| Last Modified: | 08 Nov 2021 20:56 |
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