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Further N-Terminal Sequences in Human Hemoglobins A, S and F by Edman's Phenylthiohydantoin Method

Shelton, J. Roger and Schroeder, W. A. (1960) Further N-Terminal Sequences in Human Hemoglobins A, S and F by Edman's Phenylthiohydantoin Method. Journal of the American Chemical Society, 82 (13). pp. 3342-3345. ISSN 0002-7863. http://resolver.caltech.edu/CaltechAUTHORS:20181119-161053564

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Abstract

By means of the Edman phenylthiohydantoin method, the N-terminal sequences in the peptide chains of several human hemoglobins have been found to be as follows: α^A and α^F, val-leu-ser-pro-ala-aspNH_2-; β^A, val-his-leu-thr-pro-glu-; β^S, val-his-leu-thr-pro-val-; and γ^F, gly-his-phe.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1021/ja01498a028DOIArticle
Additional Information:© 1960 American Chemical Society. Received January 4, 1960. We wish to thank Joan E. Balog for her work in separating the polypeptide chains of hemoglobin and Dr. G. Matsuda and Dr. R. T. Jones for procurement and preparation of hemoglobin solutions. This investigation was supported in part by a grant (H-2258) from the National Institutes of Health, United States Public Health Service.
Funders:
Funding AgencyGrant Number
NIHH-2258
Other Numbering System:
Other Numbering System NameOther Numbering System ID
Division of Chemistry and Chemical Engineering2508
Record Number:CaltechAUTHORS:20181119-161053564
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20181119-161053564
Official Citation:Further N-Terminal Sequences in Human Hemoglobins A, S and F by Edman's Phenylthiohydantoin Method J. Roger Shelton and W. A. Schroeder Journal of the American Chemical Society 1960 82 (13), 3342-3345 DOI: 10.1021/ja01498a028
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:91057
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:20 Nov 2018 15:57
Last Modified:20 Nov 2018 15:57

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