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Simulation study of ultrasound-modulated optical tomography

Yao, Gang and Wang, Lihong V. (2001) Simulation study of ultrasound-modulated optical tomography. In: Biomedical Optoacoustics II. Proceedings of SPIE. No.4256. Society of Photo-optical Instrumentation Engineers (SPIE) , Bellingham, WA, pp. 192-199. ISBN 9780819439345. https://resolver.caltech.edu/CaltechAUTHORS:20181207-161547522

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Abstract

Monte-Carlo modeling technique was used to simulate the ultrasound-modulated optical tomography. The difference between absorption and scattering objects was compared. Simulation result indicated that this technique is sensitive to object absorption property, while the scattering properties have less effect on the output AC/DC signal intensity. It was also demonstrated that inhomogeneity and the background optical properties of the scattering medium could change the AC/DC value. The signal-to-noise ratio problem in the experiment is carefully analyzed. The major noise source is the speckle noise caused by the small particle movement within the tissue sample. The decorrelation time of the speckle pattern was measured in the tissue sample. In order to reduce the speckle noise, the data acquisition time must be less than the speckle decorrelation time.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1117/12.429307DOIArticle
ORCID:
AuthorORCID
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2001 Society of Photo-Optical Instrumentation Engineers (SPIE). This project was sponsored in part by National Institutes of Health grants R29 CA68562, R01 CA71980, and R21 CA83760, National Science Foundation grant BES-9734491, and Texas Higher Education Coordinating Board grant 000512-0123-1999.
Funders:
Funding AgencyGrant Number
NIHR29 CA68562
NIHR01 CA71980
NIHR21 CA83760
NSFBES-9734491
Texas Higher Education Coordinating Board000512-0123-1999
Subject Keywords:optical imaging, ultrasound modulation, biological tissue
Series Name:Proceedings of SPIE
Issue or Number:4256
Record Number:CaltechAUTHORS:20181207-161547522
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20181207-161547522
Official Citation:Gang Yao, Lihong V. Wang, "Simulation study of ultrasound-modulated optical tomography," Proc. SPIE 4256, Biomedical Optoacoustics II, (15 June 2001); doi: 10.1117/12.429307
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:91598
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:10 Dec 2018 22:55
Last Modified:03 Oct 2019 20:36

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