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Ultrasound-modulated laser tomography

Wang, Lihong V. and Yao, Gang (2001) Ultrasound-modulated laser tomography. In: Saratov Fall Meeting 2000: Optical Technologies in Biophysics and Medicine II. Proceedings of SPIE. No.4241. Society of Photo-optical Instrumentation Engineers (SPIE) , Bellingham, WA, pp. 1-5.

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An ultrasonic beam was focused into a biological tissue sample to modulate the laser light passing through the ultrasonic beam inside the tissue. The speckle field formed by the transmitted laser light was detected by a CCD camera with the source-synchronous-illumination lock-in technique. The ultrasound-modulated laser light reflects the local optical and mechanical properties within the ultrasonic beam and can be used for tomographic imaging of the tissue. Spatial resolution along the ultrasonic axis was achieved by sweeping the ultrasonic frequency. Two-dimensional images of biological tissue were successfully obtained with both single frequency modulation and frequency-swept modulation. Three-dimensional images could be acquired as well in principle.

Item Type:Book Section
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URLURL TypeDescription Section
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2001 Society of Photo-Optical Instrumentation Engineers (SPIE).
Subject Keywords:optical imaging, ultrasound modulation, biological tissue
Series Name:Proceedings of SPIE
Issue or Number:4241
Record Number:CaltechAUTHORS:20181207-161547762
Persistent URL:
Official Citation:Lihong V. Wang, Gang Yao, "Ultrasound-modulated laser tomography," Proc. SPIE 4241, Saratov Fall Meeting 2000: Optical Technologies in Biophysics and Medicine II, (4 May 2001); doi: 10.1117/12.431526
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:91601
Deposited By: George Porter
Deposited On:10 Dec 2018 23:25
Last Modified:16 Nov 2021 03:42

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