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Ultrasound-modulated optical tomography for dense turbid media

Wang, Lihong and Zhao, Xuemei and Jacques, Steven L. (1996) Ultrasound-modulated optical tomography for dense turbid media. In: Biomedical Sensing, Imaging, and Tracking Technologies I. Proceedings of SPIE. No.2676. Society of Photo-optical Instrumentation Engineers (SPIE) , Bellingham, WA, pp. 91-102. ISBN 9780819420503. http://resolver.caltech.edu/CaltechAUTHORS:20181207-161549324

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Abstract

Continuous-wave ultrasonic modulation of scattered laser light has been used to image objects in tissue-simulating turbid media for the first time. We hypothesized that the ultrasound wave focused into the turbid media modulates the laser light passing through the ultrasonic focal zone. The modulated laser light collected by a photomultiplier tube reflects the local mechanical and optical properties in the focal zone. Buried objects in 5-cm thick tissue phantoms (absorption coefficient µ_a = 0.1 cm^(-1), reduced scattering coefficient µ_s' = 10 cm^(-1)) were located with millimeter resolution by scanning and detecting alterations of the ultrasound-modulated optical signal.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1117/12.238787DOIArticle
ORCID:
AuthorORCID
Wang, Lihong0000-0001-9783-4383
Additional Information:© 1996 Society of Photo-Optical Instrumentation Engineers (SPIE). The project was sponsored in part by The University of Texas M.D. Anderson Cancer Center grant, The Whitaker Foundation grant, Department of Energy grant, and National Institutes of Health grant.
Funders:
Funding AgencyGrant Number
University of TexasUNSPECIFIED
Whitaker FoundationUNSPECIFIED
Department of Energy (DOE)UNSPECIFIED
NIHUNSPECIFIED
Subject Keywords:Ultrasound-modulation, optical imaging, optical tomography, turbid media, scattering media, biological tissue phantoms
Record Number:CaltechAUTHORS:20181207-161549324
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20181207-161549324
Official Citation:Lihong V. Wang, Xuemei Zhao, Steven L. Jacques, "Ultrasound-modulated optical tomography for dense turbid media," Proc. SPIE 2676, Biomedical Sensing, Imaging, and Tracking Technologies I, (24 April 1996); doi: 10.1117/12.238787
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:91619
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:11 Dec 2018 22:57
Last Modified:11 Dec 2018 22:57

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