Stephens, Dawn V. and Tittel, Frank and Wang, Lihong and Hielscher, Andreas and Jacques, Steven (1994) Detection of an object inside a phantom tissue using a spatial filter. In: Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases. Proceedings of SPIE. No.2135. Society of Photo-optical Instrumentation Engineers (SPIE) , Bellingham, WA, pp. 200-208. ISBN 9780819414304. https://resolver.caltech.edu/CaltechAUTHORS:20181207-161550642
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Abstract
We report the detection of an object inside a phantom tissue using a spatial filter and a 5-mW He-Ne Laser. The phantom tissue is composed of 8% scattering polystyrene spheres and is diluted to different concentrations in water. The solution is placed inside of a cuvette of length 5 cm and width 5 cm. The spatial filter, composed of a 4-cm plano-convex lens and a 10-micrometers pinhole, is able to extract ballistic and quasi-ballistic photons from the transmitted light. A photomultiplier tube is used for detection, and a lock-in amplifier is used to reduce the amount of noise in the signal. We are able to detect the object in a phantom tissue of 20 mean free paths [mfp] with a contrast of 99.0%. The contrast in a tissue with 30 mfp is 22.7%.
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| Additional Information: | © 1994 Society of Photo-Optical Instrumentation Engineers (SPIE). This research was performed as a summer internship cooperative between Rice University and UT MD Anderson Cancer Center in Houston, Texas. The author wishes to thank the Center for Theoretical Study of Physical Systems at Clark Atlanta University, the Rice Quantum Institute, and the Spend a Summer with a Scientist Program at Rice University for their financial contributions. | ||||||||
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| Series Name: | Proceedings of SPIE | ||||||||
| Issue or Number: | 2135 | ||||||||
| Record Number: | CaltechAUTHORS:20181207-161550642 | ||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20181207-161550642 | ||||||||
| Official Citation: | Dawn V. Stephens, Frank K. Tittel, Lihong V. Wang, Andreas H. Hielscher, Steven L. Jacques, "Detection of an object inside a phantom tissue using a spatial filter," Proc. SPIE 2135, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases, (19 May 1994); doi: 10.1117/12.175994 | ||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||
| ID Code: | 91633 | ||||||||
| Collection: | CaltechAUTHORS | ||||||||
| Deposited By: | George Porter | ||||||||
| Deposited On: | 12 Dec 2018 15:45 | ||||||||
| Last Modified: | 03 Oct 2019 20:36 |
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