A Caltech Library Service

Optimizing Bone Scaffold Porosity Distributions

Poh, Patrina S. P. and Valainis, Dvina and Bhattacharya, Kaushik and van Griensven, Martijn and Dondl, Patrick (2018) Optimizing Bone Scaffold Porosity Distributions. . (Submitted)

[img] PDF - Submitted Version
See Usage Policy.


Use this Persistent URL to link to this item:


We consider a simple one-dimensional time-dependent model for bone regeneration in the presence of a bio-resorbable polymer scaffold. Within the framework of the model, we optimize the effective mechanical stiffness of the polymer scaffold together with the regenerated bone matrix. The result of the optimization procedure is a scaffold porosity distribution which maximizes the stiffness of the scaffold-bone system over the regeneration time, such that the propensity for mechanical failure is reduced.

Item Type:Report or Paper (Discussion Paper)
Related URLs:
URLURL TypeDescription Paper
Bhattacharya, Kaushik0000-0003-2908-5469
van Griensven, Martijn0000-0001-5104-9881
Additional Information:PSP Poh and P Dondl contributed equally to this work.
Record Number:CaltechAUTHORS:20190123-111634389
Persistent URL:
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:92428
Deposited By: Tony Diaz
Deposited On:23 Jan 2019 20:04
Last Modified:09 Mar 2020 13:19

Repository Staff Only: item control page