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Distribution of Proflavin-Induced Mutations in the Genetic Fine Structure

Brenner, S. and Benzer, S. and Barnett, L. (1958) Distribution of Proflavin-Induced Mutations in the Genetic Fine Structure. Nature, 182 (4641). pp. 983-985. ISSN 0028-0836. doi:10.1038/182983a0.

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We have investigated mutation in the same genetic material induced by proflavin which had been shown by De Mars to be mutagenic in phage. Proflavin is known to interact with deoxyribonucleic acid but, unlike 5-bromouracil, does not appear to become incorporated. Comparison of the distribution of r_II mutations induced by proflavin and by 5-bromouracil shows that these two mutagens act on completely different groups of sites in the genetic structure.

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Additional Information:© 1958 Nature Publishing Group.
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Issue or Number:4641
Record Number:CaltechAUTHORS:20190301-162720976
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:93410
Deposited By: George Porter
Deposited On:04 Mar 2019 16:03
Last Modified:16 Nov 2021 16:57

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