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On the mechanism of photoreactivation of ultraviolet-inactivated bacteriophage

Lennox, E. S. and Luria, S. E. and Benzer, S. (1954) On the mechanism of photoreactivation of ultraviolet-inactivated bacteriophage. Biochimica et Biophysica Acta, 15 (4). pp. 471-474. ISSN 0006-3002. doi:10.1016/0006-3002(54)90003-7.

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Phage-bacterium complexes of phages T2 and T7 on Escherichia coli B were inactivated by UV, photoreactivated, and then subjected to a second UV irradiation. Photoreactivated complexes had the same sensitivity to UV as reactivated complexes at the same survival level. This result is in agreement with the hypothesis that photoreactivation is effected by a direct reversal of the primary UV damage, rather than by a by-pass mechanism which circumvents the effect of the damage.

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Additional Information:© 1954 Elsevier. Received 14 July 1954. Supported by grants-in-aid from the American Cancer Society upon recommendation of the Committee of Growth of the National Research Council and by the Michigan Memorial Phenix Project.
Funding AgencyGrant Number
American Cancer SocietyUNSPECIFIED
Michigan Memorial Phenix ProjectUNSPECIFIED
National Foundation for Infantile ParalysisUNSPECIFIED
Issue or Number:4
Record Number:CaltechAUTHORS:20190301-163726489
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Official Citation:E.S. Lennox, S.E. Luria, S. Benzer, On the mechanism of photoreactivation of ultraviolet-inactivated bacteriophage, Biochimica et Biophysica Acta, Volume 15, Issue 4, 1954, Pages 471-474, ISSN 0006-3002, (
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:93411
Deposited By: George Porter
Deposited On:04 Mar 2019 16:05
Last Modified:16 Nov 2021 16:57

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