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Study of ultrasound-modulated optical tomography in biological tissue with parallel detection

Yao, Gang and Wang, Lihong V. (2000) Study of ultrasound-modulated optical tomography in biological tissue with parallel detection. In: Proceedings of the 22nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE , Piscataway, NJ, pp. 2317-2320. ISBN 0780364651. http://resolver.caltech.edu/CaltechAUTHORS:20190304-143523911

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Abstract

An ultrasonic beam was focused into a biological tissue sample to modulate the laser light passing through the ultrasonic beam inside the tissue. The speckle field formed by the transmitted laser light was detected by a CCD camera with the source-synchronous-illumination lock-in technique. The ultrasound-modulated laser light reflects the local optical and mechanical properties within the ultrasonic beam and can be used for tomographic imaging of the tissue. Spatial resolution along the ultrasonic axis was achieved by sweeping the ultrasonic frequency. Two-dimensional images of biological tissue were successfully obtained with both single frequency modulation and frequency-swept modulation. Three-dimensional images could be acquired as well in principle.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1109/iembs.2000.900606DOIArticle
ORCID:
AuthorORCID
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2000 IEEE. This project was sponsored in part by the National Institutes of Health grants R29 CA68562, R01 CA71980, and R21 CA83760 and by the National Science Foundation grant BES-9734491.
Funders:
Funding AgencyGrant Number
NIHR29 CA68562
NIHR01 CA71980
NIHR21 CA83760
NSFBES-9734491
Subject Keywords:optical imaging, ultrasound modulation, biological tissue
Record Number:CaltechAUTHORS:20190304-143523911
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20190304-143523911
Official Citation:G. Yao and L. V. Wang, "Study of ultrasound-modulated optical tomography in biological tissue with parallel detection," Proceedings of the 22nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (Cat. No.00CH37143), Chicago, IL, 2000, pp. 2317-2320 vol.3. doi: 10.1109/IEMBS.2000.900606
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:93468
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:05 Mar 2019 18:16
Last Modified:05 Mar 2019 18:16

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