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Angular-spectrum modeling of focusing light inside scattering media by optical phase conjugation

Yang, Jiamiao and Li, Jingwei and He, Sailing and Wang, Lihong V. (2019) Angular-spectrum modeling of focusing light inside scattering media by optical phase conjugation. Optica, 6 (3). pp. 250-256. ISSN 2334-2536. PMCID PMC7002031. doi:10.1364/optica.6.000250.

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Focusing light inside scattering media by optical phase conjugation has been intensively investigated due to its potential applications, such as in deep tissue imaging. However, no existing physical models explain the impact of the various factors on the focusing performance inside a dynamic scattering medium. Here, we establish an angular-spectrum model to trace the field propagation during the entire optical phase conjugation process in the presence of scattering media. By incorporating fast decorrelation components, the model enables us to investigate the competition between the guide star and fast tissue motions for photon tagging. Other factors affecting the focusing performance are also analyzed via the model. As a proof of concept, we experimentally verify our model in the case of focusing light through dynamic scattering media. This angular-spectrum model allows analysis of a series of scattering events in highly scattering media and benefits related applications.

Item Type:Article
Related URLs:
URLURL TypeDescription CentralArticle
Yang, Jiamiao0000-0003-0006-8411
Li, Jingwei0000-0003-4927-1066
He, Sailing0000-0002-3401-1125
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreement. Received 28 November 2018; revised 24 January 2019; accepted 29 January 2019 (Doc. ID 353065); published 27 February 2019. We thank Dr. Lei Gong, Dr. Yan Liu, Lei Li, and Dr. Yuecheng Shen for insightful discussions on the work. Funding: National Institutes of Health (NIH) (DP1 EB016986, R01 CA186567, U01 NS099717).
Funding AgencyGrant Number
NIHDP1 EB016986
NIHR01 CA186567
NIHU01 NS099717
Issue or Number:3
PubMed Central ID:PMC7002031
Record Number:CaltechAUTHORS:20190304-152755762
Persistent URL:
Official Citation:Jiamiao Yang, Jingwei Li, Sailing He, and Lihong V. Wang, "Angular-spectrum modeling of focusing light inside scattering media by optical phase conjugation," Optica 6, 250-256 (2019)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:93477
Deposited By: George Porter
Deposited On:05 Mar 2019 19:31
Last Modified:16 Feb 2022 00:56

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