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High-resolution photoacoustic microscope for rat brain imaging in vivo

Yang, Xiaoquan and Cai, Xin and Maslov, Konstantin and Wang, Lihong V. and Luo, Qingming (2010) High-resolution photoacoustic microscope for rat brain imaging in vivo. Chinese Optics Letters, 8 (6). pp. 609-611. ISSN 1671-7694. https://resolver.caltech.edu/CaltechAUTHORS:20190306-084226548

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Abstract

A reflection-mode photoacoustic microscope (PAM) for rat brain imaging in vivo is constructed. A pulsed laser is used as an excitation source, and a focused ultrasound transducer is adopted to collect the photoacoustic signal. Raster scanning is applied to acquire three-dimensional (3D) data. The obtained measurements of the lateral and axial resolutions of the microscope are 45 and 15 \mu m, respectively. The imaging depth in the chicken breast tissue is 3.1 mm at a signal-to-noise ratio (SNR) of 20 dB without any signal averaging. The imaging speed is 30 A-line/s. Experimental results in vivo demonstrate the capability of 3D imaging of the brain vessels of the rat after removing the skull.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://www.osapublishing.org/col/abstract.cfm?uri=col-8-6-609PublisherArticle
ORCID:
AuthorORCID
Maslov, Konstantin0000-0003-3408-8840
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2010 Chinese Optics Letters.
Issue or Number:6
Record Number:CaltechAUTHORS:20190306-084226548
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20190306-084226548
Official Citation:Xiaoquan Yang, Xin Cai, Konstantin Maslov, Lihong Wang, and Qingming Luo, "High-resolution photoacoustic microscope for rat brain imaging in vivo," Chin. Opt. Lett. 8, 609-611 (2010)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:93570
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:06 Mar 2019 16:47
Last Modified:03 Mar 2020 13:01

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