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Flexible and superwettable bands as a platform toward sweat sampling and sensing

He, Xuecheng and Xu, Tailin and Gu, Zhen and Gao, Wei and Xu, Li-Ping and Pan, Tingrui and Zhang, Xueji (2019) Flexible and superwettable bands as a platform toward sweat sampling and sensing. Analytical Chemistry, 91 (7). pp. 4296-4300. ISSN 0003-2700. http://resolver.caltech.edu/CaltechAUTHORS:20190318-084935045

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Abstract

Wearable biosensors as a user-friendly measurement platform have become a rapidly growing field of interests due to their possibility in integrating traditional medical diagnostics and healthcare management into miniature lab-on-body analytic devices. This paper demonstrates a flexible and skin-mounted band that combines superhydrophobic-superhydrophilic microarrays with nanodendritic colorimetric biosensors toward in situ sweat sampling and analysis. Particularly, on the superwettable bands, the superhydrophobic background could confine microdroplets into superhydrophilic microwells. On-body investigations further reveal that the secreted sweat is repelled by the superhydrophobic silica coating and precisely collected and sampled onto the superhydrophilic micropatterns with negligible lateral spreading, which provides an independent “vessel” toward cellphone-based sweat biodetection (pH, chloride, glucose and calcium). Such wearable, superwettable band-based biosensors with improved interface controllability could significantly enhance epidemical sweat sampling in well-defined sites, holding a great promise for facile and noninvasive biofluids analysis.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1021/acs.analchem.8b05875DOIArticle
https://pubs.acs.org/doi/suppl/10.1021/acs.analchem.8b05875PublisherSupporting Information
ORCID:
AuthorORCID
Xu, Tailin0000-0003-4037-2856
Gu, Zhen0000-0003-2947-4456
Gao, Wei0000-0002-8503-4562
Xu, Li-Ping0000-0002-2683-7963
Zhang, Xueji0000-0002-0035-3821
Additional Information:© 2019 American Chemical Society. Received: December 21, 2018; Accepted: March 18, 2019; Published: March 18, 2019. We acknowledge funding from National Natural Science Foundation of China (Grants 21804007, 21890740, and 21890742), Beijing Natural Science Foundation (Grant 2184109), Fundamental Research Funds for Central Universities (Grant FRF-TP-17-066A1), National Postdoctoral Innovative Talents Support Program of China (Grant BX20180036), Program for Guangdong Introducing Innovative and Entrepreneurial Teams (Grant 2016ZT06D631), and the Shenzhen Fundamental Research Program (Grant JCYJ20170413164102261). The authors declare no competing financial interest.
Funders:
Funding AgencyGrant Number
National Natural Science Foundation of China21804007
National Natural Science Foundation of China21890740
National Natural Science Foundation of China21890742
Beijing Natural Science Foundation2184109
Fundamental Research Funds for Central UniversitiesFRF-TP-17-066A1
National Postdoctoral Innovative Talents Support Program of ChinaBX20180036
Program for Guangdong Introducing Innovative and Entrepreneurial Teams2016ZT06D631
Shenzhen Fundamental Research ProgramJCYJ20170413164102261
Record Number:CaltechAUTHORS:20190318-084935045
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20190318-084935045
Official Citation:Flexible and Superwettable Bands as a Platform toward Sweat Sampling and Sensing. Xuecheng He, Tailin Xu, Zhen Gu, Wei Gao, Li-Ping Xu, Tingrui Pan, and Xueji Zhang. Analytical Chemistry 2019 91 (7), 4296-4300. DOI: 10.1021/acs.analchem.8b05875
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:93906
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:18 Mar 2019 15:57
Last Modified:05 Apr 2019 21:10

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