Tirrell, David Anthony (2019) Award Address (Ronald Breslow Award for Achievement in Biomimetic Chemistry sponsored by the Ronald Breslow Award Endowment). Reinterpreting the Genetic Code: Non-Canonical Amino Acids in Protein Science and Engineering. In: 257th ACS National Meeting & Exposition, 31 March - 4 April 2019, Orlando, FL. https://resolver.caltech.edu/CaltechAUTHORS:20190325-085114527
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Abstract
The genetic code, elucidated in the 1960s through the work of Nirenberg, Ochoa, Khorana and their coworkers, provides a set of mol. instructions for translating nucleic acids into proteins. Through the efforts of our lab. and others, the code has been "reinterpreted" in various ways to allow the participation of an expanded set of amino acids in cellular protein synthesis. These developments have enabled powerful new approaches to protein design and to time-resolved, state-selective, and cell-selective anal. of protein synthesis in complex biol. systems.
| Item Type: | Conference or Workshop Item (Paper) | ||||||
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| Additional Information: | © 2019 American Chemical Society. | ||||||
| Record Number: | CaltechAUTHORS:20190325-085114527 | ||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20190325-085114527 | ||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||
| ID Code: | 94094 | ||||||
| Collection: | CaltechAUTHORS | ||||||
| Deposited By: | Tony Diaz | ||||||
| Deposited On: | 25 Mar 2019 15:56 | ||||||
| Last Modified: | 03 Oct 2019 21:00 |
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