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Advances in embryo selection methods

Ajduk, Anna and Zernicka-Goetz, Magdalena (2012) Advances in embryo selection methods. F1000 Biology Reports, 4 . Art. No. 11. ISSN 1757-594X. PMCID PMC3369238. doi:10.3410/b4-11. https://resolver.caltech.edu/CaltechAUTHORS:20190417-152710123

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Abstract

Despite many recent advances in the field of reproductive biology and medicine, the efficiency of in vitro fertilization procedures remains relatively low. There is a need for a reliable and non-invasive method of embryo selection to ensure that only embryos with the highest developmental potential are chosen for transfer to mothers-to-be. Here, we compare various methods currently used for assessing embryonic viability, such as examination of embryonic morphology, quality of the genetic material, or metabolism. Additionally, we discuss novel procedures for embryonic assessment based on advanced time-lapse imaging techniques, which show great promise and may lead to increased in vitro fertilization efficiencies.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.3410/b4-11DOIArticle
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369238/PubMed CentralArticle
ORCID:
AuthorORCID
Zernicka-Goetz, Magdalena0000-0002-7004-2471
Additional Information:This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/legalcode), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes. The method of assessing embryo developmental potential based on analysis of the cytoplasmic movements is the subject of a patent application filed in the U.S. by Magdalena Zernicka-Goetz and Anna Ajduk (US application no. 61/503827).
PubMed Central ID:PMC3369238
DOI:10.3410/b4-11
Record Number:CaltechAUTHORS:20190417-152710123
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20190417-152710123
Official Citation:Ajduk A, Zernicka-Goetz M. Advances in embryo selection methods. F1000 Biol Rep. 2012;4:11. doi:10.3410/B4-11
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:94762
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:17 Apr 2019 22:38
Last Modified:16 Nov 2021 17:07

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