Pine, Jerome and Maher, Michael and Potter, Steven and Tai, Yu-Chong and Tatic-Lucic, Svetlana and Wright, John and Buzsaki, Gyorgy and Bragin, Anatol (1996) A cultured neuron probe. In: Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.5. IEEE , Piscataway, NJ, pp. 2133-2135. ISBN 0780338111. https://resolver.caltech.edu/CaltechAUTHORS:20190429-151824904
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Abstract
Work in progress toward the creation of a "cultured neuron probe" is described. This is a silicon structure similar to that for a multielectrode probe, but with embedded neurons which are intended to grow out and integrate with the neurons of a host nervous system into which the probe has been inserted. Each probe neuron is in close proximity to an electrode which is designed for extracellular estimation and recording from the probe neuron. In this way the probe neurons may provide a highly specific long-term communication link between external electronics and the host. Initial experiments to establish the feasibility of the concept will be done in rat hippocampus.
| Item Type: | Book Section | |||||||||
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| Additional Information: | © 1996 IEEE. This work is supported by the U. S. National Institutes of Health, Neural Prosthesis Program. | |||||||||
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| DOI: | 10.1109/iembs.1996.646466 | |||||||||
| Record Number: | CaltechAUTHORS:20190429-151824904 | |||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20190429-151824904 | |||||||||
| Official Citation: | J. Pine et al., "A cultured neuron probe," Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Amsterdam, 1996, pp. 2133-2135 vol.5. doi: 10.1109/IEMBS.1996.646466 | |||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | |||||||||
| ID Code: | 95090 | |||||||||
| Collection: | CaltechAUTHORS | |||||||||
| Deposited By: | George Porter | |||||||||
| Deposited On: | 30 Apr 2019 14:10 | |||||||||
| Last Modified: | 16 Nov 2021 17:10 |
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