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A cultured neuron probe

Pine, Jerome and Maher, Michael and Potter, Steven and Tai, Yu-Chong and Tatic-Lucic, Svetlana and Wright, John and Buzsaki, Gyorgy and Bragin, Anatol (1996) A cultured neuron probe. In: Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.5. IEEE , Piscataway, NJ, pp. 2133-2135. ISBN 0780338111. http://resolver.caltech.edu/CaltechAUTHORS:20190429-151824904

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Abstract

Work in progress toward the creation of a "cultured neuron probe" is described. This is a silicon structure similar to that for a multielectrode probe, but with embedded neurons which are intended to grow out and integrate with the neurons of a host nervous system into which the probe has been inserted. Each probe neuron is in close proximity to an electrode which is designed for extracellular estimation and recording from the probe neuron. In this way the probe neurons may provide a highly specific long-term communication link between external electronics and the host. Initial experiments to establish the feasibility of the concept will be done in rat hippocampus.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1109/iembs.1996.646466DOIArticle
https://ieeexplore.ieee.org/document/646466PublisherArticle
ORCID:
AuthorORCID
Maher, Michael0000-0003-0577-3726
Tai, Yu-Chong0000-0001-8529-106X
Additional Information:© 1996 IEEE. This work is supported by the U. S. National Institutes of Health, Neural Prosthesis Program.
Funders:
Funding AgencyGrant Number
NIHUNSPECIFIED
Record Number:CaltechAUTHORS:20190429-151824904
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20190429-151824904
Official Citation:J. Pine et al., "A cultured neuron probe," Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Amsterdam, 1996, pp. 2133-2135 vol.5. doi: 10.1109/IEMBS.1996.646466
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:95090
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:30 Apr 2019 14:10
Last Modified:30 Apr 2019 14:10

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