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[The phenomenon of RNA interference and development of organism]

Aravin, A. A. and Vagin, V. V. and Naumova, N. M. and Rozovskiĭ, Ia. M. and Klenov, M. S. and Gvozdev, V. A. (2002) [The phenomenon of RNA interference and development of organism]. Ontogenez, 33 (5). pp. 349-360. ISSN 0475-1450. https://resolver.caltech.edu/CaltechAUTHORS:20190506-144851787

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Abstract

[Article in Russian] RNA interference consists in specific mRNA degradation in response to introduction of a double-stranded RNA, homologous in nucleotide sequence. RNA interference was found in eukaryotes and is used in genomics as a powerful method to determine the functions of genes with known nucleotide sequences. RNA interference is considered as a tool of protection against viruses and harmful consequences of mobile elements' transposals. The involvement of the components of RNA interference is considered in spermatogenesis of Drosophila melanogaster and regulation of the expression of genes in Caenorhabditis elegans responsible for temporal patterns of development. The role of RNQA interference in stem cell formation and functioning is also considered.


Item Type:Article
Issue or Number:5
Record Number:CaltechAUTHORS:20190506-144851787
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20190506-144851787
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:95261
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:06 May 2019 22:09
Last Modified:03 Oct 2019 21:11

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