A Caltech Library Service

High mutation frequency induced by hybridization

Sturtevant, A. H. (1939) High mutation frequency induced by hybridization. Proceedings of the National Academy of Sciences of the United States of America, 25 (7). pp. 308-310. ISSN 0027-8424. PMCID PMC1077910. doi:10.1073/pnas.25.7.308.

PDF - Published Version
See Usage Policy.


Use this Persistent URL to link to this item:


The increase in variability that is a familiar result of the rearing of second generations from crosses between different races is certainly due chiefly to segregation and recombination of genes in which the parental races differed. There is, however, a persistent feeling that perhaps interracial crossing also induces the production of new mutations. The first attempt to test this view experimentally with Drosophila led to negative results (Duncan 1915). Belgovsky (1937) reported an increased frequency of somatic mutations in the hybrids between D. melanogaster and D. simulans, in x-ray experiments. The differences reported were not very striking, and in any case have little bearing on questions concerning spontaneous frequencies.

Item Type:Article
Related URLs:
URLURL TypeDescription CentralArticle
Additional Information:© 1939 by the National Academy of Sciences. Communicated June 13, 1939.
Issue or Number:7
PubMed Central ID:PMC1077910
Record Number:CaltechAUTHORS:STUpnas39b
Persistent URL:
Official Citation:High Mutation Frequency Induced by Hybridization A. H. Sturtevant Proceedings of the National Academy of Sciences Jul 1939, 25 (7) 308-310; DOI: 10.1073/pnas.25.7.308
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:9532
Deposited By: Tony Diaz
Deposited On:30 Jan 2008
Last Modified:08 Nov 2021 21:00

Repository Staff Only: item control page