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Nematode Postembryonic Cell Lineages

Horvitz, H. Robert and Sternberg, Paul W. (1982) Nematode Postembryonic Cell Lineages. Journal of Nematology, 14 (2). pp. 240-248. ISSN 0022-300X. PMCID PMC2618157. https://resolver.caltech.edu/CaltechAUTHORS:20190515-113500751

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Abstract

The complete postembryonic ceil lineages of the free-living nentatodes Caenorhabditis elegans and Panagrellus redivivus are known. Postembryonic cell divisions lead to substantial increases in the number of cells and, in most cases, in the number of types of cells in the neuronal, muscular, hypodermal, and digestive systems. The patterns of postembyronic cell divisions are essentially invariant and generate a fixed number of progeny cells of strictly specified fates. Cell fates depend upon both lineage history and cell-cell interactions: lineage limits the developmental potential of each cell and, for certain cells, cell-cell interactions specify which of a small number of alternative potential fates is acquired. Relatively simple differences in cell lineage account for some of the striking differences in gross morphology both between sexes and between species. Genetic studies indicate that these cell lineage differences reflect one or a few relatively simple mutational events. Interspecific differences in cell lineage are likely to be good indicators of evolutionary distance and may be helpful in defining taxonomic relationships. Both the techniques utilized in, and the information acquired from, studies of cell lineages in C. elegam and P. redivivus may prove useful to other hematologists. Key words: Caenorhabditis elegans, Panagrellus redivivus, anatomy, development, taxonomy, evolution.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://journals.fcla.edu/jon/article/view/65369PublisherArticle
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2618157PubMed CentralArticle
ORCID:
AuthorORCID
Sternberg, Paul W.0000-0002-7699-0173
Additional Information:© 1982 The Society of Nematologists. Received for publication 22 September 1981. Symposium presented at the annual meeting of the Society of Nematologists, Seattle, Washington, August 1981.
Subject Keywords:Caenorhabditis elegans, Panagrellus redivivus, anatomy, development, taxonomy, evolution
Issue or Number:2
PubMed Central ID:PMC2618157
Record Number:CaltechAUTHORS:20190515-113500751
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20190515-113500751
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:95514
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:16 May 2019 02:40
Last Modified:03 Oct 2019 21:14

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