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Cognitive neural prosthetics

Andersen, R. A. and Burdick, J. W. and Musallam, S. and Pesaran, B. and Cham, J. G. (2004) Cognitive neural prosthetics. Trends in Cognitive Sciences, 8 (11). pp. 486-493. ISSN 1364-6613. doi:10.1016/j.tics.2004.09.009.

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Research on neural prosthetics has focused largely on using activity related to hand trajectories recorded from motor cortical areas. An interesting question revolves around what other signals might be read out from the brain and used for neural prosthetic applications. Recent studies indicate that goals and expected value are among the high-level cognitive signals that can be used and will potentially enhance the ability of paralyzed patients to communicate with the outside world. Other new findings show that local field potentials provide an excellent source of information about the cognitive state of the subject and are much easier to record and maintain than spike activity. Finally, new movable probe technologies will enable recording electrodes to seek out automatically the best signals for decoding cognitive variables.

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Andersen, R. A.0000-0002-7947-0472
Additional Information:© 2004 Elsevier Ltd. Available online 6 October 2004. We wish to thank Eddie Branchaud, Grant Mulliken, Yu-Chong Tai, Brian Corneil, Hans Scherberger, Bradley Greger, Daniella Meeker, Igor Fineman, Zoran Nenadic, Dan Rizzuto and Hilary Glidden for insightful discussions and participation in experiments described in this article. We acknowledge the support of the National Eye Institute, the Defense Advanced Research Projects Agency, the Office of Naval Research, the Boswell Foundation, the National Science Foundation, the Christopher Reeve Paralysis Foundation, the Sloan-Swartz Center for Theoretical Neurobiology at Caltech, and the Human Frontier Science Program. We thank Tessa Yao for administrative assistance, Betty Grieve, Kelsie Pajsa and Lea Martel for technical support, Viktor Shcherbatyuk for computer support, and Janet Baer and Claire Lindsell for veterinary care.
Funding AgencyGrant Number
National Eye InstituteUNSPECIFIED
Defense Advanced Research Projects Agency (DARPA)UNSPECIFIED
Office of Naval Research (ONR)UNSPECIFIED
James G. Boswell FoundationUNSPECIFIED
Christopher Reeve Paralysis FoundationUNSPECIFIED
Sloan-Swartz Center for Theoretical NeurobiologyUNSPECIFIED
Human Frontier Science ProgramUNSPECIFIED
Issue or Number:11
Record Number:CaltechAUTHORS:20190617-134136047
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Official Citation:R.A. Andersen, J.W. Burdick, S. Musallam, B. Pesaran, J.G. Cham, Cognitive neural prosthetics, Trends in Cognitive Sciences, Volume 8, Issue 11, 2004, Pages 486-493, ISSN 1364-6613, (
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:96474
Deposited By: Tony Diaz
Deposited On:17 Jun 2019 21:25
Last Modified:16 Nov 2021 17:21

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