CaltechAUTHORS
  A Caltech Library Service

Efficiency of polymerase chain reaction processes: A stochastic model

Hassibi, Arjang and Sharif, Masoud (2006) Efficiency of polymerase chain reaction processes: A stochastic model. In: IEEE International Workshop on Genomic Signal Processing and Statistics, 2006 (GENSIPS '06), College Station, TX, 28-30 May 2006. IEEE , Piscataway, NJ, pp. 35-36. ISBN 1-4244-0385-5. https://resolver.caltech.edu/CaltechAUTHORS:HASgensips06

[img]
Preview
PDF
See Usage Policy.

559Kb

Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:HASgensips06

Abstract

A stochastic model for the efficiency of polymerase chain reaction (PCR) processes is presented. The model is based on the assumption that the i’th nucleotide incorporation on the DNA template takes τi seconds, where τi has an exponential distribution with mean 1/λi. In this paper, given λi that can be obtained from the primer-template sequence, temperature profile, enzyme rate, and other assay conditions [3], we calculate the efficiency of a multi-step PCR process using the distribution of the summation of non-identical exponential distributions.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1109/GENSIPS.2006.353143DOIUNSPECIFIED
Additional Information:© Copyright 2006 IEEE. Reprinted with permission. Publication Date: May 2006. Posted online: 2007-04-30.
Record Number:CaltechAUTHORS:HASgensips06
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:HASgensips06
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:9697
Collection:CaltechAUTHORS
Deposited By: Archive Administrator
Deposited On:05 Mar 2008
Last Modified:03 Oct 2019 00:02

Repository Staff Only: item control page