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Ed Carstensen, advisor and mentor to the shockwave lithotripsy program project group

McAteer, James and Evan, Andrew P. and Lingeman, James E. and Willis, Lynn R. and Blomgren, Philip M. and Williams, James C. and Handa, Rajash and Connors, Bret A. and Crum, Lawrence and Bailey, Michael and Matula, Tom and Khokhlova, Vera A. and Sapozhnikov, Oleg A. and Cleveland, Robin and Colonius, Tim and Pishchalnikov, Yuri A. (2017) Ed Carstensen, advisor and mentor to the shockwave lithotripsy program project group. In: 3rd Joint Meeting of the Acoustical Society of America and the European Acoustics Association, 25-29 June 2017, Boston, MA.

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In the 1980s shockwave lithotripsy emerged as a revolutionary advancement for the treatment of kidney stones. Initial studies with patients showed SWL to be highly effective. The technology was elegant, outcomes exceptionally positive and early tests suggested treatment was safe. As experience with SWL grew, limitations surfaced. A key finding was that SWs have the potential to induce significant trauma to the kidney. Our group convinced the NIH it was time to conduct a rigorous assessment to characterize the adverse effects of SWL and determine the mechanisms of SW action in stone breakage and tissue injury. The NIH Program Project Grant mechanism mandated we establish a panel of external advisors to help guide our work. We needed expertise in physical acoustics, cavitation and animal models of ultrasound exposure. We wanted a leading expert. We were extremely fortunate to land Ed Carstensen. Ed worked with us for nearly 15 years, well into our third renewal cycle. He was a brilliant scientist, a man dedicated to the highest standards of conduct in research. Ed taught us a great deal, he inspired by example and had an exceptional influence on our work and on the greater field of lithotripsy research.

Item Type:Conference or Workshop Item (Paper)
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Colonius, Tim0000-0003-0326-3909
Additional Information:© Acoustical Society of America. Published Online: 10 June 2017. Work supported by NIH-DK43881.
Funding AgencyGrant Number
Subject Keywords:Diseases and conditions; Organs; Physical acoustics; Ultrasound; Shock waves; Animal model; Medical diagnosis
Record Number:CaltechAUTHORS:20190709-092102823
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:96985
Deposited By: Melissa Ray
Deposited On:12 Jul 2019 20:26
Last Modified:16 Nov 2021 17:25

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