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The Integration of Positron Emission Tomography With Magnetic Resonance Imaging

Cherry, Simon R. and Louie, Angelique Y. and Jacobs, Russell E. (2008) The Integration of Positron Emission Tomography With Magnetic Resonance Imaging. Proceedings of the IEEE, 96 (3). pp. 416-438. ISSN 0018-9219. https://resolver.caltech.edu/CaltechAUTHORS:CHEprocieee08

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Abstract

A number of laboratories and companies are currently exploring the development of integrated imaging systems for magnetic resonance imaging (MRI) and positron emission tomography (PET). Scanners for both preclinical and human research applications are being pursued. In contrast to the widely distributed and now quite mature PET/computed tomography technology, most PET/MRI designs allow for simultaneous rather than sequential acquisition of PET and MRI data. While this offers the possibility of novel imaging strategies, it also creates considerable challenges for acquiring artifact-free images from both modalities. This paper discusses the motivation for developing combined PET/MRI technology, outlines the obstacles in realizing such an integrated instrument, and presents recent progress in the development of both the instrumentation and of novel imaging agents for combined PET/MRI studies. The performance of the first-generation PET/MRI systems is described. Finally, a range of possible biomedical applications for PET/MRI are outlined.


Item Type:Article
ORCID:
AuthorORCID
Jacobs, Russell E.0000-0002-1382-8486
Additional Information:© Copyright 2008 IEEE. Reprinted with permission. Manuscript received June 1, 2007. [Posted online: 2008-02-12] This work was supported in part by the National Institutes of Health under Grants R01 EB000993 and U24 RR021760 and the Gordon and Betty Moore Foundation.
Funders:
Funding AgencyGrant Number
National Institute of Biomedical Imaging and BioengineeringR01 EB000993
National Center for Research Resources (NCRR)U24 RR021760
Gordon and Betty Moore FoundationUNSPECIFIED
Subject Keywords:Biomedical imaging; magnetic resonance imaging; multimodality imaging; positron emission tomography
Issue or Number:3
Record Number:CaltechAUTHORS:CHEprocieee08
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:CHEprocieee08
Alternative URL:http://dx.doi.org/10.1109/JPROC.2007.913502
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:9729
Collection:CaltechAUTHORS
Deposited By: Archive Administrator
Deposited On:11 Mar 2008
Last Modified:03 Oct 2019 00:03

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