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Navigating the chemical space of amide activation to drug discovery

Baker-Tripp, Emma (2019) Navigating the chemical space of amide activation to drug discovery. In: 258th ACS National Meeting & Exposition, 25-29 August 2019, San Diego, CA. https://resolver.caltech.edu/CaltechAUTHORS:20190812-085312348

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Abstract

This presentation will describe my scientific journey from graduate school to industry. My doctoral research at UCLA focused on the development of nickel-catalyzed reactions of amides. In particular, the Suzuki-Miyaura coupling, esterification, and transamidation of amide substrates will be described. These studies demonstrate that amides, despite classically being considered inert substrates, can be harnessed as synthons for use in the construction of C-heteroatom and C-C bonds via non-precious metal catalysis. After an abbreviated tenure in a post-doctoral position, I made the exciting decision to transition to a start-up drug discovery company where I am now a medicinal chemist working in small mol. drug discovery.


Item Type:Conference or Workshop Item (Paper)
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https://www.acs.org/content/acs/en/meetings/national-meeting.htmlOrganizationConference Website
Additional Information:© 2019 American Chemical Society.
Record Number:CaltechAUTHORS:20190812-085312348
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20190812-085312348
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:97747
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:12 Aug 2019 17:41
Last Modified:03 Oct 2019 21:34

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