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Chemical approaches toward a quantitative, systems-level understanding of protein O-GlcNAcylation signaling networks

Hsieh-Wilson, Linda C. (2019) Chemical approaches toward a quantitative, systems-level understanding of protein O-GlcNAcylation signaling networks. In: 258th ACS National Meeting & Exposition, 25-29 August 2019, San Diego, CA. https://resolver.caltech.edu/CaltechAUTHORS:20190812-135544133

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Abstract

The dynamic posttranslational modification of proteins by O-linked-b-N-acetylglucosamine (O-GlcNAcylation) plays many diverse roles in cellular physiol. and disease. Here we will describe a quant., systems-level approach for studying the function, specificity, and dynamic regulation of O-GlcNAcylation. Elucidation of the signaling networks assocd. with the O-GlcNAc modification provides new insights into its central functions and may reveal new therapeutic approaches to enable its selective modulation.


Item Type:Conference or Workshop Item (Paper)
Related URLs:
URLURL TypeDescription
https://www.acs.org/content/acs/en/meetings/national-meeting.htmlOrganizationConference Website
ORCID:
AuthorORCID
Hsieh-Wilson, Linda C.0000-0001-5661-1714
Additional Information:© 2019 American Chemical Society.
Record Number:CaltechAUTHORS:20190812-135544133
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20190812-135544133
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:97786
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:12 Aug 2019 21:02
Last Modified:03 Oct 2019 21:35

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