Hsieh-Wilson, Linda C. (2019) Chemical approaches toward a quantitative, systems-level understanding of protein O-GlcNAcylation signaling networks. In: 258th ACS National Meeting & Exposition, 25-29 August 2019, San Diego, CA. https://resolver.caltech.edu/CaltechAUTHORS:20190812-135544133
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Abstract
The dynamic posttranslational modification of proteins by O-linked-b-N-acetylglucosamine (O-GlcNAcylation) plays many diverse roles in cellular physiol. and disease. Here we will describe a quant., systems-level approach for studying the function, specificity, and dynamic regulation of O-GlcNAcylation. Elucidation of the signaling networks assocd. with the O-GlcNAc modification provides new insights into its central functions and may reveal new therapeutic approaches to enable its selective modulation.
| Item Type: | Conference or Workshop Item (Paper) | ||||||
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| Additional Information: | © 2019 American Chemical Society. | ||||||
| Record Number: | CaltechAUTHORS:20190812-135544133 | ||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20190812-135544133 | ||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||
| ID Code: | 97786 | ||||||
| Collection: | CaltechAUTHORS | ||||||
| Deposited By: | Tony Diaz | ||||||
| Deposited On: | 12 Aug 2019 21:02 | ||||||
| Last Modified: | 03 Oct 2019 21:35 |
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