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Innovation by Evolution: Bringing New Chemistry to Life (Nobel Lecture)

Arnold, Frances H. (2019) Innovation by Evolution: Bringing New Chemistry to Life (Nobel Lecture). Angewandte Chemie International Edition, 58 (41). pp. 14420-14426. ISSN 1433-7851. doi:10.1002/anie.201907729. https://resolver.caltech.edu/CaltechAUTHORS:20190821-144026374

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Abstract

The directed evolution of enzymes is now routinely used to develop new catalysts with various applications, such as in environmentally friendly production of chemicals and renewable fuels. In her Nobel lecture, F. Arnold describes how lessons from nature inspired the development of methods for directed evolution.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1002/anie.201907729DOIArticle
ORCID:
AuthorORCID
Arnold, Frances H.0000-0002-4027-364X
Additional Information:© 2019 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim. Issue Online: 27 September 2019; Version of Record online: 21 August 2019; Manuscript received: 21 June 2019. I thank the Royal Swedish Academy of Sciences, my family, friends, colleagues, Sabine Brinkmann‐Chen, Cheryl Nakashima, and especially my current and former students. I am grateful to the California Institute of Technology, where I was inspired to explore the unknown for new understanding and found the team with which to do it.
Subject Keywords:biocatalysis; enzymes; directed evolution; synthetic methods; protein engineering
Issue or Number:41
DOI:10.1002/anie.201907729
Record Number:CaltechAUTHORS:20190821-144026374
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20190821-144026374
Official Citation:F. H. Arnold, Angew. Chem. Int. Ed. 2019, 58, 14420. https://doi.org/10.1002/anie.201907729
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:98085
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:21 Aug 2019 21:44
Last Modified:16 Nov 2021 17:36

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