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Principles of open source bioinstrumentation applied to the poseidon syringe pump system

Booeshaghi, A. Sina and da Veiga Beltrame, Eduardo and Bannon, Dylan and Gehring, Jase and Pachter, Lior (2019) Principles of open source bioinstrumentation applied to the poseidon syringe pump system. Scientific Reports, 9 . Art. No. 12385. ISSN 2045-2322. PMCID PMC6711986. https://resolver.caltech.edu/CaltechAUTHORS:20190827-103540654

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Abstract

The poseidon syringe pump and microscope system is an open source alternative to commercial systems. It costs less than $400 and can be assembled in under an hour using the instructions and source files available at https://pachterlab.github.io/poseidon. We describe the poseidon system and use it to illustrate design principles that can facilitate the adoption and development of open source bioinstruments. The principles are functionality, robustness, safety, simplicity, modularity, benchmarking, and documentation.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1038/s41598-019-48815-9DOIArticle
https://doi.org/10.1101/521096DOIDiscussion Paper
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711986PubMed CentralArticle
https://github.com/pachterlab/poseidonRelated ItemData
ORCID:
AuthorORCID
Booeshaghi, A. Sina0000-0002-6442-4502
da Veiga Beltrame, Eduardo0000-0002-1529-9207
Gehring, Jase0000-0002-3894-9495
Pachter, Lior0000-0002-9164-6231
Alternate Title:Design principles for open source bioinstrumentation: the poseidon syringe pump system as an example
Additional Information:© 2019 The Author(s). This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. Received 07 February 2019; Accepted 08 August 2019; Published 27 August 2019. Data Availability: Testing data is available at https://github.com/pachterlab/poseidon. We thank Nicolas Bray and Kersh Theva for testing prototypes of the poseidon system and for valuable feedback. Thanks to Shannon Hateley for initial help with 3D printing and Zaid Adel Zayyad for designing the icons in Fig. 5. Author Contributions: J.G. conceived of the project and developed the initial design for the syringe pumps. A.S.B. designed the syringe pump system and microscope, and implemented the poseidon software. E.V.B. helped with the design the poseidon system and oversaw hardware printing and design. A.S.B. and E.V.B. tested the poseidon system. J.G., A.S.B. and E.V.B. formulated the design principles. D.B. developed an initial version of the software. A.S.B., E.V.B., J.G. and L.P. wrote the manuscript. The authors declare no competing interests.
Subject Keywords:Lab-on-a-chip; Mechanical engineering
PubMed Central ID:PMC6711986
Record Number:CaltechAUTHORS:20190827-103540654
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20190827-103540654
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:98267
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:27 Aug 2019 17:47
Last Modified:20 Jul 2020 16:33

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