CaltechAUTHORS
  A Caltech Library Service

Dual-Function Intravascular Catheter for Atherosclerosis Diagnostics

Luo, Yuan and Abiri, Parinaz and Packard, Rene R. S. and Hsiai, Tzung K. and Tai, Yu-Chong (2019) Dual-Function Intravascular Catheter for Atherosclerosis Diagnostics. In: 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII). IEEE , Piscataway, NJ, pp. 625-628. ISBN 9781538681046. https://resolver.caltech.edu/CaltechAUTHORS:20190829-100211037

Full text is not posted in this repository. Consult Related URLs below.

Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:20190829-100211037

Abstract

We herein present a novel intravascular catheter, with dual-functions of electrical impedance spectroscopy (EIS) and flow fraction reserve (FFR), validated in live pig animal for atherosclerosis/plaques diagnostics. FFR has been the standard tool in determining plaque vulnerability yet could produce false negative results when stenosis is relatively small. Meanwhile, EIS has been demonstrated to specifically distinguish the lipid-rich pool, the signifying feature of rupture-prone plaques. The synergetic performance of these two functionalities can significantly enhance state-of-art diagnostics accuracy for atherosclerosis.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1109/transducers.2019.8808540DOIArticle
ORCID:
AuthorORCID
Packard, Rene R. S.0000-0002-8520-5843
Hsiai, Tzung K.0000-0003-1734-0792
Tai, Yu-Chong0000-0001-8529-106X
Additional Information:© 2019 IEEE. This study was supported by National Institutes of Health grants HL118650 (T.K.H., Y.C.T.), HL083015 (T.K.H.), HL111437 (T.K.H., Y.C.T.). The authors also want to thank colleagues from Caltech MEMS Lab and Cardiovascular Engineering Lab in UCLA for their kind help and fruitful discussion throughout this work.
Funders:
Funding AgencyGrant Number
NIHHL118650
NIHHL083015
NIHHL111437
Subject Keywords:Atherosclerosis, Intravascular detection, Fractional Flow Reserve, Electrochemical Impedance Spectroscopy
Record Number:CaltechAUTHORS:20190829-100211037
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20190829-100211037
Official Citation:Y. Luo, P. Abiri, R. R. S. Packard, T. K. Hsiai and Y. Tai, "Dual-Function Intravascular Catheter for Atherosclerosis Diagnostics," 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII), Berlin, Germany, 2019, pp. 625-628. doi: 10.1109/TRANSDUCERS.2019.8808540
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:98335
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:30 Aug 2019 15:23
Last Modified:25 Nov 2019 23:53

Repository Staff Only: item control page