Luo, Yuan and Abiri, Parinaz and Packard, Rene R. S. and Hsiai, Tzung K. and Tai, Yu-Chong (2019) Dual-Function Intravascular Catheter for Atherosclerosis Diagnostics. In: 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII). IEEE , Piscataway, NJ, pp. 625-628. ISBN 9781538681046. https://resolver.caltech.edu/CaltechAUTHORS:20190829-100211037
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Abstract
We herein present a novel intravascular catheter, with dual-functions of electrical impedance spectroscopy (EIS) and flow fraction reserve (FFR), validated in live pig animal for atherosclerosis/plaques diagnostics. FFR has been the standard tool in determining plaque vulnerability yet could produce false negative results when stenosis is relatively small. Meanwhile, EIS has been demonstrated to specifically distinguish the lipid-rich pool, the signifying feature of rupture-prone plaques. The synergetic performance of these two functionalities can significantly enhance state-of-art diagnostics accuracy for atherosclerosis.
| Item Type: | Book Section | ||||||||
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| Additional Information: | © 2019 IEEE. This study was supported by National Institutes of Health grants HL118650 (T.K.H., Y.C.T.), HL083015 (T.K.H.), HL111437 (T.K.H., Y.C.T.). The authors also want to thank colleagues from Caltech MEMS Lab and Cardiovascular Engineering Lab in UCLA for their kind help and fruitful discussion throughout this work. | ||||||||
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| Subject Keywords: | Atherosclerosis, Intravascular detection, Fractional Flow Reserve, Electrochemical Impedance Spectroscopy | ||||||||
| DOI: | 10.1109/transducers.2019.8808540 | ||||||||
| Record Number: | CaltechAUTHORS:20190829-100211037 | ||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20190829-100211037 | ||||||||
| Official Citation: | Y. Luo, P. Abiri, R. R. S. Packard, T. K. Hsiai and Y. Tai, "Dual-Function Intravascular Catheter for Atherosclerosis Diagnostics," 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII), Berlin, Germany, 2019, pp. 625-628. doi: 10.1109/TRANSDUCERS.2019.8808540 | ||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||
| ID Code: | 98335 | ||||||||
| Collection: | CaltechAUTHORS | ||||||||
| Deposited By: | George Porter | ||||||||
| Deposited On: | 30 Aug 2019 15:23 | ||||||||
| Last Modified: | 16 Nov 2021 17:38 |
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