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Double-Ballooned Local Drug Delivery Catheter with Blood Bypassing Function

Huang, Zi-Yu and Luo, Yuan and Abiri, Parinaz and Packard, Rene R. S. and Hsiai, Tzung K. and Tai, Yu-Chong (2019) Double-Ballooned Local Drug Delivery Catheter with Blood Bypassing Function. In: 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII). IEEE , Piscataway, NJ, pp. 2213-2216. ISBN 9781538681046. https://resolver.caltech.edu/CaltechAUTHORS:20190829-100211144

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Abstract

We present a double-ballooned catheter that enables both local drug delivery and blood bypassing at the same time. Such catheters are targeted for high-dose local drug treatment of cardiovascular diseases, such as atherosclerosis and restenosis, allowing for extended use without causing downstream ischemia. The device is composed of two flexible balloons that can isolate the lesion under inflation. Local drug delivery can be achieved using the inner catheters while a blood bypassing catheter allows for continuous blood flow. The functionalities of the catheter are validated in both benchtop and live pig experiments.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1109/transducers.2019.8808417DOIArticle
ORCID:
AuthorORCID
Packard, Rene R. S.0000-0002-8520-5843
Hsiai, Tzung K.0000-0003-1734-0792
Tai, Yu-Chong0000-0001-8529-106X
Additional Information:© 2019 IEEE. This study was supported by National Institutes of Health grants HL118650 (T.K.H., Y.C.T.), HL083015 (T.K.H.), HL111437 (T.K.H., Y.C.T.)
Funders:
Funding AgencyGrant Number
NIHHL118650
NIHHL083015
NIHHL111437
Subject Keywords:Local Drug Delivery, Blood Bypassing, Double- Ballooned Catheter
Record Number:CaltechAUTHORS:20190829-100211144
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20190829-100211144
Official Citation:Z. Huang, Y. Luo, P. Abiri, R. R. S. Packard, T. K. Hsiai and Y. Tai, "Double-Ballooned Local Drug Delivery Catheter with Blood Bypassing Function," 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII), Berlin, Germany, 2019, pp. 2213-2216. doi: 10.1109/TRANSDUCERS.2019.8808417
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:98336
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:30 Aug 2019 14:50
Last Modified:25 Nov 2019 23:54

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