Huang, Zi-Yu and Luo, Yuan and Abiri, Parinaz and Packard, Rene R. S. and Hsiai, Tzung K. and Tai, Yu-Chong (2019) Double-Ballooned Local Drug Delivery Catheter with Blood Bypassing Function. In: 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII). IEEE , Piscataway, NJ, pp. 2213-2216. ISBN 9781538681046. https://resolver.caltech.edu/CaltechAUTHORS:20190829-100211144
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Abstract
We present a double-ballooned catheter that enables both local drug delivery and blood bypassing at the same time. Such catheters are targeted for high-dose local drug treatment of cardiovascular diseases, such as atherosclerosis and restenosis, allowing for extended use without causing downstream ischemia. The device is composed of two flexible balloons that can isolate the lesion under inflation. Local drug delivery can be achieved using the inner catheters while a blood bypassing catheter allows for continuous blood flow. The functionalities of the catheter are validated in both benchtop and live pig experiments.
| Item Type: | Book Section | ||||||||
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| Additional Information: | © 2019 IEEE. This study was supported by National Institutes of Health grants HL118650 (T.K.H., Y.C.T.), HL083015 (T.K.H.), HL111437 (T.K.H., Y.C.T.) | ||||||||
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| Subject Keywords: | Local Drug Delivery, Blood Bypassing, Double- Ballooned Catheter | ||||||||
| DOI: | 10.1109/transducers.2019.8808417 | ||||||||
| Record Number: | CaltechAUTHORS:20190829-100211144 | ||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20190829-100211144 | ||||||||
| Official Citation: | Z. Huang, Y. Luo, P. Abiri, R. R. S. Packard, T. K. Hsiai and Y. Tai, "Double-Ballooned Local Drug Delivery Catheter with Blood Bypassing Function," 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII), Berlin, Germany, 2019, pp. 2213-2216. doi: 10.1109/TRANSDUCERS.2019.8808417 | ||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||
| ID Code: | 98336 | ||||||||
| Collection: | CaltechAUTHORS | ||||||||
| Deposited By: | George Porter | ||||||||
| Deposited On: | 30 Aug 2019 14:50 | ||||||||
| Last Modified: | 16 Nov 2021 17:38 |
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