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Nucleotide Sequence of a Human Immunoglobulin Cγ4 Gene

Ellison, J. and Buxbaum, J. and Hood, L. (1981) Nucleotide Sequence of a Human Immunoglobulin Cγ4 Gene. DNA, 1 (1). pp. 11-18. ISSN 0198-0238.

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We report the nucleotide sequence of a gene encoding the constant region of a human immunoglobulin γ4 heavy chain (C_(γ4)). These data represent the first complete sequence determination of a human CH gene. As expected from structural studies of mouse C_γ genes, the coding sequences for the CH domains and hinge segment are separated from one another by intervening DNA sequences. Comparison with genomic sequences of the mouse C_(γ1), C_(γ2a), and C_(γ2b) genes shows conservation of the sequences in the constant region domains and the 3′ untranslated region surrounding the presumed site of poly(A) addition.

Item Type:Article
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Hood, L.0000-0001-7158-3678
Additional Information:© 1981 Mary Ann Liebert, Inc., publishers.
Issue or Number:1
Record Number:CaltechAUTHORS:20190918-082509549
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Official Citation:Nucleotide Sequence of a Human Immunoglobulin Cγ4 Gene. J. ELLISON, J. BUXBAUM, and L. HOOD. DNA 1981 1:1, 11-18.
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:98708
Deposited By: Tony Diaz
Deposited On:18 Sep 2019 20:02
Last Modified:03 Oct 2019 21:43

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