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Utilisation of MMW Radiation to Facilitate Apoptosis in Triple Negative Breast Cancer Cell Lines via TRPV1 Receptor Sensitization

Sorolla, Anabel and Romanenko, Sergii and Siegel, Peter H. and Wallace, Vincent (2019) Utilisation of MMW Radiation to Facilitate Apoptosis in Triple Negative Breast Cancer Cell Lines via TRPV1 Receptor Sensitization. In: 2019 44th International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz). IEEE , Piscataway, NJ, pp. 1-2. ISBN 9781538682852. https://resolver.caltech.edu/CaltechAUTHORS:20191025-124827099

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Abstract

Triple-negative breast cancers (TNBC) are highly aggressive malignancies comprising ~15-20 % of all breast cancers. TNBCs quickly acquire drug resistance mechanisms and are inherently resistant to radiotherapy, which significantly limits therapeutic options. Thus, there is a need to develop more selective and efficient therapeutic approaches to target this cancer subtype. In this study we investigate the applicability of MMW radiation as co-factor for prolonged sensitisation of TRPV1 receptor to promote the maximal channel activation with minimal tachyphylaxis to increase cancer cell death in TNBC.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1109/irmmw-thz.2019.8873881DOIArticle
ORCID:
AuthorORCID
Siegel, Peter H.0000-0002-2539-4646
Additional Information:© 2019 IEEE.
Record Number:CaltechAUTHORS:20191025-124827099
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20191025-124827099
Official Citation:A. Sorolla, S. Romanenko, P. H. Siegel and V. Wallace, "Utilisation of MMW Radiation to Facilitate Apoptosis in Triple Negative Breast Cancer Cell Lines via TRPV1 Receptor Sensitization," 2019 44th International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz), Paris, France, 2019, pp. 1-2. doi: 10.1109/IRMMW-THz.2019.8873881
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:99451
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:25 Oct 2019 20:09
Last Modified:25 Oct 2019 20:09

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