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Development of Gas Permeable Parylene HT as a Substrate for Cell-Culture-on-a-Chip Applications

Scianmarello, Nicholas and Cook, Colin and Shang, Kuang-Ming and Tai, Y. C. (2019) Development of Gas Permeable Parylene HT as a Substrate for Cell-Culture-on-a-Chip Applications. In: 2019 IEEE 32nd International Conference on Micro Electro Mechanical Systems (MEMS). IEEE , Piscataway, NJ, pp. 511-514. ISBN 9781728116105. https://resolver.caltech.edu/CaltechAUTHORS:20191025-124827265

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Abstract

Here we report on the production of highly gas permeable Parylene HT through a cryogenic deposition process. The unique combination of biological and chemical inertness of Parylene, and gas permeability of this porous variant make it interesting for cell culture and biology-on-a-chip applications. The dependence of porosity, density, and permeability on the deposition temperature allows for tunable control of material properties. Culture of HEK-293 cells on cryogenically deposited Parylene HT demonstrates viability for biological applications.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1109/memsys.2019.8870854DOIArticle
ORCID:
AuthorORCID
Cook, Colin0000-0002-6283-5105
Tai, Y. C.0000-0001-8529-106X
Additional Information:© 2019 IEEE.
Record Number:CaltechAUTHORS:20191025-124827265
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20191025-124827265
Official Citation:N. Scianmarello, C. Cook, K. Shang and Y. C. Tai, "Development of Gas Permeable Parylene HT as a Substrate for Cell-Culture-on-a-Chip Applications," 2019 IEEE 32nd International Conference on Micro Electro Mechanical Systems (MEMS), Seoul, Korea (South), 2019, pp. 511-514. doi: 10.1109/MEMSYS.2019.8870854
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:99453
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:25 Oct 2019 20:22
Last Modified:25 Oct 2019 20:22

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